C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: nitric oxide synthase 1, neuronal
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000086451 Nos1-003 ENSMUSG00000029361 10090 + 5:117842186-117954364 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalLiverOvaryTestisENSMUST00000086451
Transcript ID Adrenal Liver Ovary Testis
ENSMUST00000086451 0.039±0.00 0.007±0.00 0.322±0.19 0.159±0.03

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002028 IMP regulation of sodium ion transport
GO:0003958 IBA NADPH-hemoprotein reductase activity
GO:0004517 IEA nitric-oxide synthase activity
GO:0005506 IEA iron ion binding
GO:0005516 IEA calmodulin binding
GO:0005739 ISO mitochondrion
GO:0005829 IBA cytosol
GO:0006809 IEA nitric oxide biosynthetic process
GO:0006941 IMP striated muscle contraction
GO:0007263 IBA nitric oxide mediated signal transduction
GO:0010181 IEA FMN binding
GO:0018119 IDA peptidyl-cysteine S-nitrosylation
GO:0020037 IEA heme binding
GO:0031284 IBA positive regulation of guanylate cyclase activity
GO:0042738 IMP exogenous drug catabolic process
GO:0043267 IMP negative regulation of potassium ion transport
GO:0045121 IDA membrane raft
GO:0045202 IDA synapse
GO:0045776 IBA negative regulation of blood pressure
GO:0045909 IBA positive regulation of vasodilation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0050661 IEA NADP binding
GO:0051346 IMP negative regulation of hydrolase activity
GO:0051926 IMP negative regulation of calcium ion transport
GO:0055114 IEA:IBA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000317775 NOS1-001 protein_coding Homo_sapiens 0 4796
ENST00000338101 NOS1-002 protein_coding Homo_sapiens 0 2641
ENST00000344089 NOS1-201 protein_coding Homo_sapiens 0 4806
ENST00000618760 NOS1-202 protein_coding Homo_sapiens 0 2641

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