C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eukaryotic translation initiation factor 2B, subunit 1 (alpha)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029388 Eif2b1 10090 - 5:124570213-124579131 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031334 Eif2b1-001 124570213-124579131 protein_coding
  ENSMUST00000128920 Eif2b1-002 124576811-124578992 protein_coding
  ENSMUST00000135163 Eif2b1-003 124578519-124579032 nonsense_mediated_decay
  ENSMUST00000135361 Eif2b1-005 124573731-124579075 protein_coding
  ENSMUST00000152716 Eif2b1-004 124571751-124574916 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031334ENSMUST00000135361
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031334 9.177±1.12 6.185±3.19 12.486±2.93 10.552±3.50 6.914±2.90 9.751±1.87 3.933±0.26 6.945±0.86 8.084±4.28 4.778±1.12 5.815±1.35 8.948±4.03 19.009±5.99 4.183±0.81
ENSMUST00000135361 N/A N/A N/A 4.213±0.00 N/A N/A N/A N/A 11.637±0.00 N/A 9.419±1.84 15.629±0.00 20.278±9.10 2.873±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000395 CIL_000395_0002 CGP 5:124552864-124579131
CIL_00006O CIL_00006O_0003 CGP 5:124570213-124597680

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003743 ISS translation initiation factor activity
GO:0005085 IBA guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005737 ISS cytoplasm
GO:0005851 ISS eukaryotic translation initiation factor 2B complex
GO:0005886 ISO plasma membrane
GO:0006412 IEA translation
GO:0006413 ISS translational initiation
GO:0006417 IEA regulation of translation
GO:0006446 IBA regulation of translational initiation
GO:0009408 IEA response to heat
GO:0009749 IEA response to glucose
GO:0014003 ISS oligodendrocyte development
GO:0016020 ISO membrane
GO:0019003 IEA GDP binding
GO:0030234 IEA enzyme regulator activity
GO:0032057 IEA negative regulation of translational initiation in response to stress
GO:0043434 IEA response to peptide hormone
GO:0043547 ISS positive regulation of GTPase activity
GO:0044237 IEA cellular metabolic process
GO:0050790 IEA regulation of catalytic activity
GO:0051716 ISS cellular response to stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088185 eif2b1 eukaryotic translation initiation factor 2B, subunit 1 alpha protein_coding Danio_rerio
ENSDARG00000091402 eif2b1 eukaryotic translation initiation factor 2B, subunit 1 alpha protein_coding Danio_rerio
ENSG00000111361 EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa protein_coding Homo_sapiens

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