C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: unc-51 like kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029512 Ulk1 10090 - 5:110784488-110810097 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031490 Ulk1-201 110784488-110810097 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031490
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031490 9.146±1.85 18.287±3.40 8.417±0.91 16.892±2.48 11.094±5.71 11.738±1.69 15.337±4.11 10.264±1.37 9.802±1.95 15.654±0.51 18.945±1.74 13.507±2.86 10.825±5.87 2.887±1.36

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008NO CIL_0008NO_0002 VISTA 5:110598210-111198771
CIL_0007W4 CIL_0007W4_0002 VISTA 5:110754482-111355796
CIL_00076X CIL_00076X_0002 CGP 5:110773667-110810097

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000045 IMP autophagic vacuole assembly
GO:0000407 IDA pre-autophagosomal structure
GO:0004672 IDA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005776 IEA autophagic vacuole
GO:0005829 IDA cytosol
GO:0007265 IDA Ras protein signal transduction
GO:0007409 IDA axonogenesis
GO:0008104 ISS protein localization
GO:0010506 IMP regulation of autophagy
GO:0010508 IMP positive regulation of autophagy
GO:0016020 IDA membrane
GO:0016239 IEA positive regulation of macroautophagy
GO:0017137 IEA Rab GTPase binding
GO:0019901 IPI protein kinase binding
GO:0021707 IMP cerebellar granule cell differentiation
GO:0021933 IMP radial glia guided migration of cerebellar granule cell
GO:0030659 IDA cytoplasmic vesicle membrane
GO:0031102 IEA neuron projection regeneration
GO:0031175 ISS neuron projection development
GO:0031623 IMP receptor internalization
GO:0031669 IDA cellular response to nutrient levels
GO:0032403 IEA protein complex binding
GO:0034045 IDA pre-autophagosomal structure membrane
GO:0034273 IBA ATG1/UKL1 signaling complex
GO:0042594 IDA response to starvation
GO:0043005 IDA neuron projection
GO:0043025 IDA neuronal cell body
GO:0046777 IDA protein autophosphorylation
GO:0048671 IMP negative regulation of collateral sprouting
GO:0048675 IMP axon extension
GO:0051386 IMP regulation of neurotrophin TRK receptor signaling pathway
GO:0070969 IPI ULK1-ATG13-FIP200 complex
GO:0097629 IEA extrinsic component of omegasome membrane
GO:0097632 IEA extrinsic component of pre-autophagosomal structure membrane
GO:0097635 IEA extrinsic component of autophagic vacuole membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062518 ulk1a unc-51-like kinase 1a (C. elegans) protein_coding Danio_rerio
ENSDARG00000074481 ulk1b unc-51-like kinase 1b (C. elegans) protein_coding Danio_rerio
ENSG00000177169 ULK1 unc-51 like autophagy activating kinase 1 protein_coding Homo_sapiens

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