C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal peptide peptidase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029550 Sppl3 10090 + 5:115011137-115098790 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031530 Sppl3-001 115011137-115098790 protein_coding
  ENSMUST00000128590 Sppl3-004 115082251-115088995 processed_transcript
  ENSMUST00000128678 Sppl3-002 115094757-115098256 retained_intron
  ENSMUST00000150708 Sppl3-003 115011146-115061601 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000031530ENSMUST00000128590
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000031530 26.149±7.48 23.630±2.70 22.896±2.37 23.609±11.99 21.126±6.53 35.322±2.19 11.022±2.53 17.193±0.81 9.627±2.74 37.259±2.84 4.771±0.47 51.470±21.45 18.358±5.09 28.451±12.91
ENSMUST00000128590 58.990±14.22 58.010±8.28 N/A 51.646±0.00 51.712±3.84 80.375±13.05 26.508±9.04 38.607±3.74 18.897±6.12 109.395±3.10 8.345±0.97 166.089±64.06 40.588±11.80 69.152±17.55

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZA CIL_0007ZA_0002 VISTA 5:114966986-115567561

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005791 ISS rough endoplasmic reticulum
GO:0030660 ISS Golgi-associated vesicle membrane
GO:0042500 ISS aspartic endopeptidase activity, intramembrane cleaving
GO:0042803 ISS protein homodimerization activity
GO:0071458 ISS integral component of cytoplasmic side of endoplasmic reticulum membrane
GO:0071556 ISS integral component of lumenal side of endoplasmic reticulum membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000025220 sppl3 signal peptide peptidase 3 protein_coding Danio_rerio
ENSG00000157837 SPPL3 signal peptide peptidase like 3 protein_coding Homo_sapiens

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