C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HNF1 homeobox A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029556 Hnf1a 10090 - 5:114948980-114971094 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000031535 Hnf1a-001 114948980-114971067 protein_coding
  ENSMUST00000176550 Hnf1a-002 114952579-114970844 nonsense_mediated_decay
  ENSMUST00000176911 Hnf1a-003 114950061-114970844 nonsense_mediated_decay
  ENSMUST00000184027 Hnf1a-004 114968705-114971094 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeColonKidneyLiverPlacentaENSMUST00000031535ENSMUST00000184027
Transcript ID Adipose Colon Kidney Liver Placenta
ENSMUST00000031535 N/A 5.473±0.71 7.883±2.17 3.216±1.72 2.778±0.00
ENSMUST00000184027 1.531±0.00 17.430±3.07 8.682±1.76 8.108±3.79 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001221 IEA transcription cofactor binding
GO:0001750 IGI photoreceptor outer segment
GO:0001824 IMP blastocyst development
GO:0001889 IMP liver development
GO:0001890 IGI placenta development
GO:0003677 IDA DNA binding
GO:0003690 IEA double-stranded DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IPI transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006338 IMP chromatin remodeling
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006357 IGI regulation of transcription from RNA polymerase II promoter
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006633 IMP fatty acid biosynthetic process
GO:0006699 IMP bile acid biosynthetic process
GO:0006783 IMP heme biosynthetic process
GO:0006979 IMP response to oxidative stress
GO:0008104 IMP protein localization
GO:0008134 IEA transcription factor binding
GO:0008203 IMP cholesterol metabolic process
GO:0009749 IMP response to glucose
GO:0015721 IMP bile acid and bile salt transport
GO:0015908 IMP fatty acid transport
GO:0030073 IMP insulin secretion
GO:0030111 IGI regulation of Wnt signaling pathway
GO:0030326 IGI embryonic limb morphogenesis
GO:0031018 IMP endocrine pancreas development
GO:0035623 IDA renal glucose absorption
GO:0042593 IMP glucose homeostasis
GO:0042803 IPI protein homodimerization activity
GO:0043565 IEA sequence-specific DNA binding
GO:0043691 IMP reverse cholesterol transport
GO:0044212 ISS transcription regulatory region DNA binding
GO:0045120 IDA pronucleus
GO:0045453 IGI bone resorption
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046323 IDA glucose import
GO:0046883 IMP regulation of hormone secretion
GO:0046982 IPI protein heterodimerization activity
GO:0046983 IPI protein dimerization activity
GO:0048341 IGI paraxial mesoderm formation
GO:0048608 IMP reproductive structure development
GO:0050796 IMP regulation of insulin secretion
GO:0060395 IDA SMAD protein signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009470 hnf1a HNF1 homeobox a protein_coding Danio_rerio
ENSG00000135100 HNF1A HNF1 homeobox A protein_coding Homo_sapiens

Loading