C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAS guanyl releasing protein 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030589 Rasgrp4 10090 + 7:29134854-29153961 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032811 Rasgrp4-001 29134933-29153961 protein_coding
  ENSMUST00000094617 Rasgrp4-201 29134933-29153939 protein_coding
  ENSMUST00000159351 Rasgrp4-005 29135073-29151499 nonsense_mediated_decay
  ENSMUST00000159898 Rasgrp4-004 29134982-29150978 retained_intron
  ENSMUST00000159975 Rasgrp4-002 29134933-29151615 protein_coding
  ENSMUST00000160194 Rasgrp4-006 29135006-29148547 protein_coding
  ENSMUST00000160396 Rasgrp4-007 29150196-29151619 protein_coding
  ENSMUST00000161522 Rasgrp4-008 29134854-29150291 protein_coding
  ENSMUST00000162946 Rasgrp4-003 29134933-29149316 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBreastHeartLiverLungOvaryPlacentaENSMUST00000032811ENSMUST00000159898ENSMUST00000159975ENSMUST00000161522ENSMUST00000162946
Transcript ID Adipose Breast Heart Liver Lung Ovary Placenta
ENSMUST00000032811 2.158±0.31 2.098±0.63 0.690±0.00 0.732±0.11 2.114±0.12 N/A 0.439±0.11
ENSMUST00000159898 1.867±0.00 1.750±0.00 N/A 0.980±0.30 N/A 1.103±0.00 0.800±0.20
ENSMUST00000159975 3.140±0.01 7.068±1.81 N/A 1.927±0.35 4.060±0.22 4.155±1.24 2.363±1.53
ENSMUST00000161522 N/A N/A N/A N/A N/A N/A 1.824±0.00
ENSMUST00000162946 3.323±0.00 5.002±0.24 N/A 1.545±0.38 N/A 5.718±1.81 1.553±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006UX CIL_0006UX_0002 CGP 7:29003340-29153961

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005088 ISS Ras guanyl-nucleotide exchange factor activity
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008283 ISS cell proliferation
GO:0009991 ISS response to extracellular stimulus
GO:0016020 ISS membrane
GO:0016049 ISS cell growth
GO:0030154 IEA cell differentiation
GO:0032320 ISS positive regulation of Ras GTPase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0046579 ISS positive regulation of Ras protein signal transduction
GO:0046872 IEA metal ion binding
GO:0051056 IEA regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061796 rasgrp4 RAS guanyl releasing protein 4 protein_coding Danio_rerio
ENSG00000171777 RASGRP4 RAS guanyl releasing protein 4 protein_coding Homo_sapiens

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