C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ryanodine receptor 1, skeletal muscle
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030592 Ryr1 10090 - 7:29003340-29125151 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032813 Ryr1-201 29003344-29125151 protein_coding
  ENSMUST00000179893 Ryr1-202 29003340-29125151 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032813ENSMUST00000179893
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032813 0.012±0.00 0.011±0.01 N/A 0.068±0.01 0.026±0.01 0.003±0.00 0.003±0.00 0.024±0.05 0.035±0.00 N/A 0.157±0.10 0.118±0.08 0.424±0.00
ENSMUST00000179893 0.012±0.00 0.011±0.01 0.835±0.40 11.464±11.79 0.026±0.01 0.003±0.00 0.537±0.54 0.010±0.01 1.420±1.38 259.542±27.55 0.125±0.03 0.055±0.04 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006UX CIL_0006UX_0002 CGP 7:29003340-29153961

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0002020 IPI protease binding
GO:0003151 IMP outflow tract morphogenesis
GO:0005219 IEA ryanodine-sensitive calcium-release channel activity
GO:0005245 IDA voltage-gated calcium channel activity
GO:0005262 IMP calcium channel activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005516 IEA calmodulin binding
GO:0005737 IEA cytoplasm
GO:0005790 IDA smooth endoplasmic reticulum
GO:0005886 IEA plasma membrane
GO:0005938 IEA cell cortex
GO:0006816 IDA calcium ion transport
GO:0006936 IMP muscle contraction
GO:0006937 TAS regulation of muscle contraction
GO:0014808 IMP release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0016529 IDA sarcoplasmic reticulum
GO:0019899 IPI enzyme binding
GO:0030314 IDA junctional membrane complex
GO:0030315 IDA T-tubule
GO:0031674 IEA I band
GO:0033017 IDA sarcoplasmic reticulum membrane
GO:0043234 IDA protein complex
GO:0043588 IMP skin development
GO:0043931 IMP ossification involved in bone maturation
GO:0048741 IMP skeletal muscle fiber development
GO:0051209 IMP release of sequestered calcium ion into cytosol
GO:0070062 IEA extracellular vesicular exosome
GO:0070588 IEA calcium ion transmembrane transport
GO:0071313 IMP cellular response to caffeine

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011422 ryr1a ryanodine receptor 1a (skeletal) protein_coding Danio_rerio
ENSDARG00000023797 ryr1b ryanodine receptor 1b (skeletal) protein_coding Danio_rerio
ENSG00000196218 RYR1 ryanodine receptor 1 (skeletal) protein_coding Homo_sapiens

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