C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcitonin/calcitonin-related polypeptide, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030669 Calca 10090 - 7:114631480-114636357 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000032906 Calca-201 114631480-114636357 protein_coding
  ENSMUST00000032907 Calca-202 114633298-114636357 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000032906ENSMUST00000032907
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000032906 0.326±0.12 0.165±0.05 0.047±0.02 1.187±0.66 0.321±0.12 N/A 0.027±0.01 1.123±0.19 0.032±0.03 0.345±0.23 0.484±0.25 0.027±0.00 0.317±0.00
ENSMUST00000032907 0.173±0.10 0.093±0.00 0.045±0.02 N/A 0.108±0.01 0.153±0.00 0.048±0.03 0.400±0.30 0.049±0.03 0.458±0.23 0.316±0.25 0.070±0.02 0.057±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QZ CIL_0007QZ_0002 VISTA 7:114596548-115197751

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001976 ISA neurological system process involved in regulation of systemic arterial blood pressure
GO:0001984 IMP vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure
GO:0002027 IMP regulation of heart rate
GO:0002548 IEA monocyte chemotaxis
GO:0005102 IDA receptor binding
GO:0005179 IEA hormone activity
GO:0005515 IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 ISO extracellular space
GO:0005622 IDA intracellular
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0006874 IGI cellular calcium ion homeostasis
GO:0006954 IDA inflammatory response
GO:0007189 IGI adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190 ISA activation of adenylate cyclase activity
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007218 IDA neuropeptide signaling pathway
GO:0007566 IEA embryo implantation
GO:0007568 IEA aging
GO:0007631 IDA feeding behavior
GO:0008016 IEA regulation of heart contraction
GO:0009408 IMP response to heat
GO:0030279 IMP negative regulation of ossification
GO:0030424 IDA axon
GO:0031645 IMP negative regulation of neurological system process
GO:0031716 IDA calcitonin receptor binding
GO:0032147 IEA activation of protein kinase activity
GO:0042311 IEA vasodilation
GO:0042802 IEA identical protein binding
GO:0043005 IDA neuron projection
GO:0043025 IDA neuronal cell body
GO:0043195 IDA terminal bouton
GO:0045762 IEA positive regulation of adenylate cyclase activity
GO:0045776 IMP negative regulation of blood pressure
GO:0045778 IMP positive regulation of ossification
GO:0045779 IEA negative regulation of bone resorption
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045986 IDA negative regulation of smooth muscle contraction
GO:0048240 ISA sperm capacitation
GO:0048265 IMP response to pain
GO:0050727 IEA regulation of inflammatory response
GO:0050965 IMP detection of temperature stimulus involved in sensory perception of pain
GO:0051482 IEA positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0071356 IEA cellular response to tumor necrosis factor
GO:1990090 IEA cellular response to nerve growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000110680 CALCA calcitonin-related polypeptide alpha protein_coding Homo_sapiens

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