C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: calcitonin-related polypeptide alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000110680 CALCA 9606 - 11:14966668-14972354 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331587 CALCA-001 14968501-14972354 protein_coding
  ENST00000361010 CALCA-201 14966669-14972286 protein_coding
  ENST00000396372 CALCA-003 14968706-14972273 protein_coding
  ENST00000469608 CALCA-002 14967040-14972272 nonsense_mediated_decay
  ENST00000486207 CALCA-004 14966668-14971201 protein_coding
  ENST00000494746 CALCA-005 14966671-14970016 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainHeartKidneyLiverLungOvaryTestisENST00000331587ENST00000396372ENST00000469608ENST00000486207ENST00000494746
Transcript ID Adipose Adrenal Bladder Brain Heart Kidney Liver Lung Ovary Testis
ENST00000331587 0.071±0.00 0.025±0.00 0.910±0.00 N/A N/A 4.897±0.00 4.902±0.00 N/A 0.031±0.00 N/A
ENST00000396372 N/A N/A N/A N/A N/A N/A 2.901±0.00 0.374±0.00 N/A 0.067±0.03
ENST00000469608 N/A N/A N/A N/A 0.092±0.00 N/A N/A N/A N/A N/A
ENST00000486207 0.034±0.00 N/A N/A 0.018±0.00 N/A 2.882±0.00 N/A N/A 0.015±0.00 N/A
ENST00000494746 N/A N/A N/A N/A N/A N/A N/A N/A 0.032±0.00 0.065±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000419 CIL_000419_0002 CGP 11:14877440-15082342

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001935 IDA endothelial cell proliferation
GO:0001944 IDA vasculature development
GO:0001976 IDA neurological system process involved in regulation of systemic arterial blood pressure
GO:0001984 IEA vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure
GO:0002027 IEA regulation of heart rate
GO:0002031 IDA G-protein coupled receptor internalization
GO:0002548 IDA monocyte chemotaxis
GO:0005102 IEA receptor binding
GO:0005179 IEA hormone activity
GO:0005515 IPI protein binding
GO:0005576 TAS:IEA extracellular region
GO:0005615 IDA extracellular space
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006468 IDA protein phosphorylation
GO:0006874 IEA cellular calcium ion homeostasis
GO:0006954 IEA inflammatory response
GO:0007159 IDA leukocyte cell-cell adhesion
GO:0007189 IEA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190 IDA activation of adenylate cyclase activity
GO:0007204 IDA positive regulation of cytosolic calcium ion concentration
GO:0007218 IEA neuropeptide signaling pathway
GO:0007267 TAS cell-cell signaling
GO:0007566 IDA embryo implantation
GO:0007568 IEA aging
GO:0007631 IEA feeding behavior
GO:0008016 IEA regulation of heart contraction
GO:0008217 NAS regulation of blood pressure
GO:0009408 IEA response to heat
GO:0010523 IDA negative regulation of calcium ion transport into cytosol
GO:0030279 IEA negative regulation of ossification
GO:0030424 IEA axon
GO:0030819 IDA positive regulation of cAMP biosynthetic process
GO:0031623 IDA receptor internalization
GO:0031645 IEA negative regulation of neurological system process
GO:0031716 IPI calcitonin receptor binding
GO:0032147 IDA activation of protein kinase activity
GO:0032403 IDA protein complex binding
GO:0032730 IDA positive regulation of interleukin-1 alpha production
GO:0032757 IDA positive regulation of interleukin-8 production
GO:0042311 IEA vasodilation
GO:0042802 IPI identical protein binding
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043195 IEA terminal bouton
GO:0043542 IDA endothelial cell migration
GO:0045651 IDA positive regulation of macrophage differentiation
GO:0045671 IDA negative regulation of osteoclast differentiation
GO:0045762 IDA positive regulation of adenylate cyclase activity
GO:0045776 IEA negative regulation of blood pressure
GO:0045778 IEA positive regulation of ossification
GO:0045779 IDA negative regulation of bone resorption
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045909 IDA positive regulation of vasodilation
GO:0045986 IEA negative regulation of smooth muscle contraction
GO:0048265 IEA response to pain
GO:0050727 IEA regulation of inflammatory response
GO:0050965 IEA detection of temperature stimulus involved in sensory perception of pain
GO:0051480 IDA cytosolic calcium ion homeostasis
GO:0051482 IDA positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0071356 IEA cellular response to tumor necrosis factor
GO:1990090 IEA cellular response to nerve growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000030669 Calca calcitonin/calcitonin-related polypeptide, alpha protein_coding Mus_musculus

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