C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: methyl CpG binding protein 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031393 Mecp2 10090 - X:74026592-74135363 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033770 Mecp2-002 74035288-74085690 protein_coding
  ENSMUST00000100750 Mecp2-001 74026592-74085638 protein_coding
  ENSMUST00000123362 Mecp2-003 74035289-74085609 protein_coding
  ENSMUST00000140399 Mecp2-004 74035670-74085609 protein_coding
  ENSMUST00000170481 Mecp2-201 74026828-74135363 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033770ENSMUST00000100750ENSMUST00000123362ENSMUST00000170481
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033770 N/A N/A N/A N/A N/A 1.059±0.00 N/A N/A 1.467±0.34 N/A N/A N/A 2.376±0.82 0.233±0.01
ENSMUST00000100750 1.084±0.52 1.616±0.93 1.160±0.23 3.266±1.23 1.178±0.52 1.514±0.53 0.725±0.00 0.538±0.11 0.888±0.37 2.095±0.39 1.767±0.48 1.822±1.03 0.554±0.29 0.202±0.13
ENSMUST00000123362 N/A N/A N/A N/A N/A 1.121±0.00 N/A N/A 0.754±0.16 N/A N/A N/A N/A N/A
ENSMUST00000170481 3.095±2.14 2.218±0.70 1.053±0.13 4.409±0.74 2.681±1.22 1.492±0.12 2.247±0.20 3.283±0.42 0.866±0.15 2.196±1.00 2.303±0.32 3.055±1.27 0.791±0.22 0.210±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007GC CIL_0007GC_0003 CGP X:74013914-74135363
CIL_0001LD CIL_0001LD_0002 CGP X:74026592-74150760

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000792 IDA heterochromatin
GO:0001662 IMP behavioral fear response
GO:0001666 IMP response to hypoxia
GO:0001964 IMP startle response
GO:0001976 IMP neurological system process involved in regulation of systemic arterial blood pressure
GO:0002087 IMP regulation of respiratory gaseous exchange by neurological system process
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0003729 IDA mRNA binding
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006020 IMP inositol metabolic process
GO:0006122 IMP mitochondrial electron transport, ubiquinol to cytochrome c
GO:0006342 IMP chromatin silencing
GO:0006349 IMP regulation of gene expression by genetic imprinting
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006541 IMP glutamine metabolic process
GO:0006576 IMP cellular biogenic amine metabolic process
GO:0007268 IMP synaptic transmission
GO:0007416 IMP synapse assembly
GO:0007420 IMP brain development
GO:0007585 IMP respiratory gaseous exchange
GO:0007612 IMP learning
GO:0007613 IMP memory
GO:0007616 IMP long-term memory
GO:0008104 IMP protein localization
GO:0008134 IPI transcription factor binding
GO:0008211 IMP glucocorticoid metabolic process
GO:0008284 IMP positive regulation of cell proliferation
GO:0008327 IDA methyl-CpG binding
GO:0008344 IMP adult locomotory behavior
GO:0008542 IMP visual learning
GO:0009405 IMP pathogenesis
GO:0009791 IMP post-embryonic development
GO:0010385 IDA double-stranded methylated DNA binding
GO:0010468 IDA regulation of gene expression
GO:0016358 IMP dendrite development
GO:0016571 IMP histone methylation
GO:0016573 IMP histone acetylation
GO:0019230 IMP proprioception
GO:0019233 IMP sensory perception of pain
GO:0019904 IEA protein domain specific binding
GO:0021549 IMP cerebellum development
GO:0021591 IMP ventricular system development
GO:0030182 IMP neuron differentiation
GO:0031061 IMP negative regulation of histone methylation
GO:0031175 IMP neuron projection development
GO:0032048 IMP cardiolipin metabolic process
GO:0033555 IMP multicellular organismal response to stress
GO:0035067 IMP negative regulation of histone acetylation
GO:0035176 IMP social behavior
GO:0035197 IDA siRNA binding
GO:0040029 IMP regulation of gene expression, epigenetic
GO:0042551 IMP neuron maturation
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0044822 IEA poly(A) RNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0046470 IMP phosphatidylcholine metabolic process
GO:0047485 IEA protein N-terminus binding
GO:0048167 IMP regulation of synaptic plasticity
GO:0050432 IMP catecholamine secretion
GO:0050884 IMP neuromuscular process controlling posture
GO:0050905 IMP neuromuscular process
GO:0051965 IMP positive regulation of synapse assembly
GO:0060079 IMP regulation of excitatory postsynaptic membrane potential
GO:0060291 IMP long-term synaptic potentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014218 mecp2 methyl CpG binding protein 2 protein_coding Danio_rerio
ENSG00000169057 MECP2 methyl CpG binding protein 2 protein_coding Homo_sapiens

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