C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: endothelin receptor type A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031616 Ednra 10090 - 8:77663031-77724464 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034029 Ednra-001 77663031-77724436 protein_coding
  ENSMUST00000146561 Ednra-002 77669694-77724464 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034029ENSMUST00000146561
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034029 21.200±13.64 5.591±0.33 3.208±0.53 2.762±1.68 11.415±1.33 4.644±0.59 14.112±0.93 2.212±0.38 1.893±0.90 28.339±3.16 0.672±0.09 13.712±2.29 1.339±0.56 0.921±0.31
ENSMUST00000146561 N/A 0.839±0.10 N/A N/A 1.461±0.00 0.918±0.14 N/A N/A N/A 4.243±0.34 0.109±0.00 12.348±4.25 N/A 1.022±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008H5 CIL_0008H5_0002 VISTA 8:77371733-77972642
CIL_0008OE CIL_0008OE_0002 VISTA 8:77407194-78008233
CIL_0008XF CIL_0008XF_0002 VISTA 8:77422984-78023939

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001569 IGI patterning of blood vessels
GO:0001666 IMP response to hypoxia
GO:0001701 IMP in utero embryonic development
GO:0001821 IEA histamine secretion
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0003094 IEA glomerular filtration
GO:0004930 TAS G-protein coupled receptor activity
GO:0004962 IMP endothelin receptor activity
GO:0005515 IPI protein binding
GO:0007186 TAS G-protein coupled receptor signaling pathway
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007205 IEA protein kinase C-activating G-protein coupled receptor signaling pathway
GO:0007266 IEA Rho protein signal transduction
GO:0007507 IGI heart development
GO:0007568 IEA aging
GO:0007585 IMP respiratory gaseous exchange
GO:0008217 IEA regulation of blood pressure
GO:0008284 IEA positive regulation of cell proliferation
GO:0014032 IMP neural crest cell development
GO:0014070 IEA response to organic cyclic compound
GO:0014824 IEA artery smooth muscle contraction
GO:0015758 IDA glucose transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019233 IEA sensory perception of pain
GO:0030315 IEA T-tubule
GO:0030818 IGI negative regulation of cAMP biosynthetic process
GO:0031965 IEA nuclear membrane
GO:0032496 IEA response to lipopolysaccharide
GO:0042310 IMP vasoconstriction
GO:0042482 IEA positive regulation of odontogenesis
GO:0043066 IEA negative regulation of apoptotic process
GO:0043084 IEA penile erection
GO:0043278 IEA response to morphine
GO:0045121 IEA membrane raft
GO:0048144 IEA fibroblast proliferation
GO:0048484 IEA enteric nervous system development
GO:0048659 IEA smooth muscle cell proliferation
GO:0050678 IEA regulation of epithelial cell proliferation
GO:0050729 IEA positive regulation of inflammatory response
GO:0051281 IEA positive regulation of release of sequestered calcium ion into cytosol
GO:0051482 IEA positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0051928 IEA positive regulation of calcium ion transport
GO:0060137 IEA maternal process involved in parturition
GO:0060322 IMP head development
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade
GO:0071260 IEA cellular response to mechanical stimulus
GO:0086100 IEA endothelin receptor signaling pathway
GO:0090023 IEA positive regulation of neutrophil chemotaxis
GO:0090184 IEA positive regulation of kidney development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011876 ednraa endothelin receptor type Aa protein_coding Danio_rerio
ENSDARG00000062262 ednrab endothelin receptor type Ab protein_coding Danio_rerio
ENSG00000151617 EDNRA endothelin receptor type A protein_coding Homo_sapiens

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