C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dihydrouridine synthase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031901 Dus2 10090 + 8:105991337-106053840 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034375 Dus2-001 106011507-106053819 protein_coding
  ENSMUST00000119736 Dus2-002 106011507-106053840 nonsense_mediated_decay
  ENSMUST00000138524 Dus2-003 106033390-106045992 retained_intron
  ENSMUST00000141374 Dus2-005 106011522-106030883 retained_intron
  ENSMUST00000142898 Dus2-006 105991337-106015842 protein_coding
  ENSMUST00000144904 Dus2-004 106048708-106052199 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034375ENSMUST00000119736
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034375 6.647±0.34 3.829±0.29 6.606±1.06 5.969±2.17 6.157±1.11 3.138±0.67 3.562±0.32 4.961±0.29 4.152±1.44 3.887±0.32 3.991±0.75 6.923±1.77 3.600±1.10 6.126±0.62
ENSMUST00000119736 N/A N/A N/A N/A N/A N/A N/A N/A 1.631±0.00 N/A 1.129±0.00 4.428±0.82 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004PO CIL_0004PO_0002 CGP 8:105973520-105996423
CIL_0004RT CIL_0004RT_0002 CGP 8:105984944-106053840
CIL_0000DG CIL_0000DG_0002 CGP 8:105991337-106053840

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002943 IEA tRNA dihydrouridine synthesis
GO:0003725 ISS double-stranded RNA binding
GO:0004860 ISS protein kinase inhibitor activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005783 IEA endoplasmic reticulum
GO:0006469 IEA negative regulation of protein kinase activity
GO:0017150 IEA tRNA dihydrouridine synthase activity
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0055114 IEA oxidation-reduction process
GO:0060548 ISS negative regulation of cell death

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077607 dus2 dihydrouridine synthase 2 protein_coding Danio_rerio
ENSG00000167264 DUS2 dihydrouridine synthase 2 protein_coding Homo_sapiens

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