C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: tyrosine kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032175 Tyk2 10090 - 9:21104069-21127346 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000001036 Tyk2-201 21104069-21127346 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001036
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001036 12.736±0.35 9.433±0.73 8.820±3.78 4.907±1.81 18.439±3.51 14.048±2.68 3.706±0.82 4.377±2.08 4.130±2.49 11.372±2.88 1.218±0.80 8.926±3.53 4.150±2.21 4.511±0.96

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004GI CIL_0004GI_0002 CGP 9:21104069-21149906

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005131 IEA growth hormone receptor binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0016020 IEA membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0031702 IEA type 1 angiotensin receptor binding
GO:0035556 IEA intracellular signal transduction
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020326 tyk2 tyrosine kinase 2 protein_coding Danio_rerio
ENSG00000105397 TYK2 tyrosine kinase 2 protein_coding Homo_sapiens

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