C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: tyrosine kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000001036 Tyk2-201 ENSMUSG00000032175 10090 - 9:21104069-21127346 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001036
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001036 12.736±0.35 9.433±0.73 8.820±3.78 4.907±1.81 18.439±3.51 14.048±2.68 3.706±0.82 4.377±2.08 4.130±2.49 11.372±2.88 1.218±0.80 8.926±3.53 4.150±2.21 4.511±0.96

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004GI CIL_0004GI_0002 CGP 9:21104069-21149906

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005131 IEA growth hormone receptor binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0016020 IEA membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0031702 IEA type 1 angiotensin receptor binding
GO:0035556 IEA intracellular signal transduction
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264818 TYK2-201 protein_coding Homo_sapiens 0 2555
ENST00000524462 TYK2-003 protein_coding Homo_sapiens 0 2551
ENST00000524470 TYK2-016 retained_intron Homo_sapiens 0 206
ENST00000525621 TYK2-001 protein_coding Homo_sapiens 0 2555
ENST00000525976 TYK2-015 protein_coding Homo_sapiens 8e-31 137
ENST00000527481 TYK2-020 nonsense_mediated_decay Homo_sapiens 0 499
ENST00000529370 TYK2-002 protein_coding Homo_sapiens 0 1424
ENST00000529412 TYK2-021 retained_intron Homo_sapiens 0 475
ENST00000529422 TYK2-017 processed_transcript Homo_sapiens 1e-30 137
ENST00000529739 TYK2-018 protein_coding Homo_sapiens 0 514
ENST00000530220 TYK2-014 retained_intron Homo_sapiens 0 261
ENST00000530560 TYK2-019 protein_coding Homo_sapiens 0 326
ENST00000533334 TYK2-012 nonsense_mediated_decay Homo_sapiens 0 375
ENST00000592137 TYK2-022 processed_transcript Homo_sapiens 0 568

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