C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pleckstrin homology domain interacting protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032253 Phip 10090 - 9:82866159-82975516 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034787 Phip-003 82866159-82975516 protein_coding
  ENSMUST00000186089 Phip-012 82900656-82932575 nonsense_mediated_decay
  ENSMUST00000186099 Phip-017 82915816-82917609 retained_intron
  ENSMUST00000187021 Phip-004 82913079-82975426 retained_intron
  ENSMUST00000188828 Phip-002 82944504-82975416 retained_intron
  ENSMUST00000188850 Phip-011 82903443-82908965 retained_intron
  ENSMUST00000188868 Phip-010 82894031-82975408 retained_intron
  ENSMUST00000189209 Phip-013 82888903-82892188 retained_intron
  ENSMUST00000189927 Phip-014 82925848-82928151 retained_intron
  ENSMUST00000189985 Phip-009 82927158-82974268 protein_coding
  ENSMUST00000190101 Phip-006 82894612-82896092 retained_intron
  ENSMUST00000190405 Phip-007 82929966-82933032 retained_intron
  ENSMUST00000190774 Phip-005 82870322-82896372 retained_intron
  ENSMUST00000190822 Phip-016 82913689-82927119 nonsense_mediated_decay
  ENSMUST00000190838 Phip-018 82955805-82975419 retained_intron
  ENSMUST00000190936 Phip-001 82897165-82901113 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034787ENSMUST00000186089ENSMUST00000187021ENSMUST00000188828ENSMUST00000188868ENSMUST00000190774ENSMUST00000190838
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034787 2.231±0.60 1.729±0.62 0.975±0.52 3.374±0.92 2.607±0.36 0.993±0.17 1.342±0.15 1.638±0.30 0.859±0.41 3.337±0.66 0.214±0.05 2.746±0.99 1.502±0.78 0.935±0.25
ENSMUST00000186089 N/A N/A N/A 4.357±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.244±0.00
ENSMUST00000187021 N/A 3.167±0.48 N/A N/A N/A 1.197±0.56 N/A N/A 0.321±0.00 2.131±0.00 N/A 3.066±0.79 N/A N/A
ENSMUST00000188828 N/A 2.675±0.00 N/A N/A N/A 0.850±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000188868 N/A N/A N/A 2.410±0.00 N/A N/A 0.803±0.00 N/A N/A N/A N/A 11.933±0.00 2.710±0.00 1.675±0.00
ENSMUST00000190774 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.730±0.00 0.474±0.00
ENSMUST00000190838 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.586±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006GA CIL_0006GA_0002 CGP 9:82829540-82975516
CIL_000621 CIL_000621_0003 CGP 9:82866159-83146685

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005158 IEA insulin receptor binding
GO:0005634 IDA nucleus
GO:0006606 IMP protein import into nucleus
GO:0007010 IEA cytoskeleton organization
GO:0008284 IGI positive regulation of cell proliferation
GO:0008286 IDA insulin receptor signaling pathway
GO:0010800 IDA positive regulation of peptidyl-threonine phosphorylation
GO:0022604 IEA regulation of cell morphogenesis
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0040008 IMP regulation of growth
GO:0045944 ISO positive regulation of transcription from RNA polymerase II promoter
GO:0070062 IEA extracellular vesicular exosome
GO:0070577 IEA lysine-acetylated histone binding
GO:2001237 ISO negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015970 phip pleckstrin homology domain interacting protein protein_coding Danio_rerio
ENSG00000146247 PHIP pleckstrin homology domain interacting protein protein_coding Homo_sapiens

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