C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: pleckstrin homology domain interacting protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000034787 Phip-003 ENSMUSG00000032253 10090 - 9:82866159-82975516 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034787
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034787 2.231±0.60 1.729±0.62 0.975±0.52 3.374±0.92 2.607±0.36 0.993±0.17 1.342±0.15 1.638±0.30 0.859±0.41 3.337±0.66 0.214±0.05 2.746±0.99 1.502±0.78 0.935±0.25

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006GA CIL_0006GA_0002 CGP 9:82829540-82975516
CIL_000621 CIL_000621_0003 CGP 9:82866159-83146685

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005158 IEA insulin receptor binding
GO:0005634 IDA nucleus
GO:0006606 IMP protein import into nucleus
GO:0007010 IEA cytoskeleton organization
GO:0008284 IGI positive regulation of cell proliferation
GO:0008286 IDA insulin receptor signaling pathway
GO:0010800 IDA positive regulation of peptidyl-threonine phosphorylation
GO:0022604 IEA regulation of cell morphogenesis
GO:0033138 IDA positive regulation of peptidyl-serine phosphorylation
GO:0040008 IMP regulation of growth
GO:0045944 ISO positive regulation of transcription from RNA polymerase II promoter
GO:0070062 IEA extracellular vesicular exosome
GO:0070577 IEA lysine-acetylated histone binding
GO:2001237 ISO negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000138106 phip-001 protein_coding Danio_rerio 0 667
ENSDART00000008401 phip-201 protein_coding Danio_rerio 0 627
ENST00000275034 PHIP-001 protein_coding Homo_sapiens 0 9838
ENST00000373275 BRWD3-001 protein_coding Homo_sapiens 0.00000000004 77
ENST00000378026 CKAP4-001 protein_coding Homo_sapiens 0.0002 55
ENST00000473691 BRWD3-003 processed_transcript Homo_sapiens 0.00000000001 77
ENST00000479165 PHIP-002 processed_transcript Homo_sapiens 0 2082

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