C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hyperpolarization-activated, cyclic nucleotide-gated K+ 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032338 Hcn4 10090 + 9:58823512-58860955 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000034889 Hcn4-201 58823512-58860955 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034889
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034889 0.283±0.18 0.529±0.09 0.025±0.00 2.236±1.06 0.694±0.31 0.052±0.01 2.374±0.04 0.091±0.02 0.009±0.00 0.251±0.09 0.223±0.06 0.233±0.09 0.105±0.06 0.043±0.02

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 IMP in utero embryonic development
GO:0002027 IEA regulation of heart rate
GO:0005222 IMP intracellular cAMP activated cation channel activity
GO:0005248 IEA voltage-gated sodium channel activity
GO:0005249 IBA voltage-gated potassium channel activity
GO:0005515 IPI protein binding
GO:0005886 IEA plasma membrane
GO:0005887 IBA integral component of plasma membrane
GO:0006812 IMP cation transport
GO:0008016 IMP regulation of heart contraction
GO:0031226 IEA intrinsic component of plasma membrane
GO:0035725 IEA sodium ion transmembrane transport
GO:0042391 IBA regulation of membrane potential
GO:0042802 IEA identical protein binding
GO:0043195 IEA terminal bouton
GO:0071320 IEA cellular response to cAMP
GO:0071321 IEA cellular response to cGMP
GO:0071805 IBA potassium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061685 hcn4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 protein_coding Danio_rerio
ENSDARG00000074419 hcn4l hyperpolarization activated cyclic nucleotide-gated potassium channel 4l protein_coding Danio_rerio
ENSG00000138622 HCN4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 protein_coding Homo_sapiens

Loading