C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein inhibitor of activated STAT 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032405 Pias1 10090 - 9:62880077-62980879 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000098651 Pias1-201 62880077-62980879 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000098651
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000098651 9.663±3.91 10.835±2.03 4.960±0.69 3.807±1.91 14.243±3.25 11.534±2.70 4.091±0.23 10.076±1.98 6.802±1.14 20.611±6.44 0.707±0.38 16.823±7.71 9.049±2.42 59.429±29.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008FO CIL_0008FO_0002 VISTA 9:62808235-63410238
CIL_00098T CIL_00098T_0002 VISTA 9:62831587-63433435
CIL_0008DX CIL_0008DX_0002 VISTA 9:62876076-63477276
CIL_00050U CIL_00050U_0002 CGP 9:62880077-63148961

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IEA DNA binding
GO:0003714 ISA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007259 ISA JAK-STAT cascade
GO:0007283 IEA spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0016605 IDA PML body
GO:0016925 IEA protein sumoylation
GO:0019789 IEA SUMO ligase activity
GO:0019899 IEA enzyme binding
GO:0019904 IEA protein domain specific binding
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032436 IMP positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0033235 ISS positive regulation of protein sumoylation
GO:0042127 IMP regulation of cell proliferation
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0051152 IEA positive regulation of smooth muscle cell differentiation
GO:0065004 IEA protein-DNA complex assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036094 PIAS1 (1 of 2) protein inhibitor of activated STAT, 1 protein_coding Danio_rerio
ENSDARG00000062445 pias1b protein inhibitor of activated STAT, 1b protein_coding Danio_rerio
ENSG00000033800 PIAS1 protein inhibitor of activated STAT, 1 protein_coding Homo_sapiens

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