C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eomesodermin homolog (Xenopus laevis)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032446 Eomes 10090 + 9:118478212-118486132 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000035020 Eomes-001 118478344-118486132 protein_coding
  ENSMUST00000111763 Eomes-003 118478212-118485366 protein_coding
  ENSMUST00000150633 Eomes-002 118478861-118482757 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035020ENSMUST00000111763ENSMUST00000150633
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035020 0.288±0.04 N/A 0.060±0.02 4.447±4.30 0.501±0.26 0.031±0.01 0.025±0.00 0.111±0.03 0.038±0.02 0.282±0.10 0.045±0.03 0.078±0.05 1.762±2.19 0.038±0.01
ENSMUST00000111763 0.191±0.14 0.060±0.03 0.023±0.01 1.540±1.49 0.431±0.14 0.052±0.01 0.088±0.04 0.062±0.06 0.011±0.01 0.125±0.06 N/A 0.110±0.06 0.179±0.01 0.042±0.02
ENSMUST00000150633 0.169±0.19 0.047±0.03 0.018±0.00 N/A 1.894±0.04 0.051±0.02 0.035±0.00 0.029±0.02 0.014±0.00 0.170±0.04 N/A 0.048±0.03 N/A 0.022±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008L2 CIL_0008L2_0002 VISTA 9:118017970-118619794

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001102 IPI RNA polymerase II activating transcription factor binding
GO:0001191 IDA RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0001706 IMP endoderm formation
GO:0001707 IMP mesoderm formation
GO:0001714 IMP endodermal cell fate specification
GO:0001824 IMP blastocyst development
GO:0001829 IDA trophectodermal cell differentiation
GO:0002302 IDA CD8-positive, alpha-beta T cell differentiation involved in immune response
GO:0003677 ISS DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005622 IDA intracellular
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0007420 IEA brain development
GO:0010002 IMP cardioblast differentiation
GO:0010468 IMP regulation of gene expression
GO:0019827 IMP stem cell maintenance
GO:0021772 IMP olfactory bulb development
GO:0021796 IMP cerebral cortex regionalization
GO:0021895 IDA cerebral cortex neuron differentiation
GO:0030154 IMP cell differentiation
GO:0032609 IDA interferon-gamma production
GO:0035914 IMP skeletal muscle cell differentiation
GO:0043565 ISO sequence-specific DNA binding
GO:0045597 IDA positive regulation of cell differentiation
GO:0045664 IMP regulation of neuron differentiation
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 ISO positive regulation of transcription from RNA polymerase II promoter
GO:0050767 IMP regulation of neurogenesis
GO:0060706 IMP cell differentiation involved in embryonic placenta development
GO:0060809 IMP mesodermal to mesenchymal transition involved in gastrulation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006640 eomesa eomesodermin homolog a protein_coding Danio_rerio
ENSDARG00000019428 eomesb eomesodermin homolog b protein_coding Danio_rerio
ENSG00000163508 EOMES eomesodermin protein_coding Homo_sapiens

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