C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: eomesodermin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000163508 EOMES 9606 - 3:27715949-27722711 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295743 EOMES-001 27715949-27722498 protein_coding
  ENST00000449599 EOMES-002 27716377-27722312 protein_coding
  ENST00000461503 EOMES-004 27718864-27722711 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000295743ENST00000449599ENST00000461503
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000295743 0.038±0.00 0.674±0.00 0.108±0.00 0.023±0.00 0.032±0.00 N/A 0.027±0.00 N/A 0.068±0.00 1.454±0.00 N/A 0.079±0.00 0.126±0.07 0.261±0.06
ENST00000449599 N/A N/A N/A N/A 0.214±0.00 0.061±0.00 0.042±0.00 0.076±0.00 0.117±0.08 0.184±0.09 0.033±0.00 0.077±0.04 0.055±0.00 N/A
ENST00000461503 0.064±0.00 N/A N/A N/A N/A 0.130±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008L2 CIL_0008L2_0001 VISTA 3:27692337-28294260
CIL_0002DZ CIL_0002DZ_0002 CGP 3:27715949-28325142

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001102 ISS RNA polymerase II activating transcription factor binding
GO:0001191 ISS RNA polymerase II transcription factor binding transcription factor activity involved in negative regulation of transcription
GO:0001706 ISS endoderm formation
GO:0001707 ISS mesoderm formation
GO:0001714 IEA endodermal cell fate specification
GO:0001824 IEA blastocyst development
GO:0001829 IEA trophectodermal cell differentiation
GO:0002302 IMP CD8-positive, alpha-beta T cell differentiation involved in immune response
GO:0003677 ISS DNA binding
GO:0003682 IEA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0007420 IMP brain development
GO:0010002 IEA cardioblast differentiation
GO:0010468 IEA regulation of gene expression
GO:0019827 IEA stem cell maintenance
GO:0021772 IEA olfactory bulb development
GO:0021796 IEA cerebral cortex regionalization
GO:0021895 IEA cerebral cortex neuron differentiation
GO:0030154 IEA cell differentiation
GO:0032609 IEA interferon-gamma production
GO:0035914 IEA skeletal muscle cell differentiation
GO:0043565 IDA sequence-specific DNA binding
GO:0045597 IEA positive regulation of cell differentiation
GO:0045664 IEA regulation of neuron differentiation
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0050767 IEA regulation of neurogenesis
GO:0060706 ISS cell differentiation involved in embryonic placenta development
GO:0060809 ISS mesodermal to mesenchymal transition involved in gastrulation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000006640 eomesa eomesodermin homolog a protein_coding Danio_rerio
ENSDARG00000019428 eomesb eomesodermin homolog b protein_coding Danio_rerio
ENSMUSG00000032446 Eomes eomesodermin homolog (Xenopus laevis) protein_coding Mus_musculus

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