C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanine nucleotide binding protein (G protein), alpha inhibiting 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000032562 Gnai2 10090 - 9:107614138-107635342 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055704 Gnai2-201 107614138-107635342 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000055704
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000055704 199.363±2.33 129.541±5.69 179.791±8.22 104.562±33.69 185.913±66.94 178.324±10.09 87.431±7.92 102.662±3.12 58.148±18.52 280.878±23.42 24.639±2.82 187.246±44.49 168.736±64.21 29.433±11.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00010B CIL_00010B_0003 CGP 9:107614138-107668968

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0001664 IBA G-protein coupled receptor binding
GO:0001973 IBA adenosine receptor signaling pathway
GO:0003924 IBA GTPase activity
GO:0004871 IBA signal transducer activity
GO:0005515 IPI protein binding
GO:0005525 ISA GTP binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005813 ISS centrosome
GO:0005829 IEA cytosol
GO:0005834 IBA heterotrimeric G-protein complex
GO:0005886 ISS plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0007049 IEA cell cycle
GO:0007193 ISA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007213 IMP G-protein coupled acetylcholine receptor signaling pathway
GO:0007214 IBA gamma-aminobutyric acid signaling pathway
GO:0008283 IPI cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0016020 IEA membrane
GO:0030496 ISS midbody
GO:0031683 IBA G-protein beta/gamma-subunit complex binding
GO:0031982 IEA vesicle
GO:0035556 IEA intracellular signal transduction
GO:0045121 IEA membrane raft
GO:0046872 IEA metal ion binding
GO:0050805 IEA negative regulation of synaptic transmission
GO:0051301 ISS cell division
GO:0051924 IEA regulation of calcium ion transport
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017294 gnai2b guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2b protein_coding Danio_rerio
ENSDARG00000018174 gnai2a guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a protein_coding Danio_rerio
ENSG00000114353 GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 protein_coding Homo_sapiens

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