C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: guanine nucleotide binding protein (G protein), alpha inhibiting 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000055704 Gnai2-201 ENSMUSG00000032562 10090 - 9:107614138-107635342 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000055704
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000055704 199.363±2.33 129.541±5.69 179.791±8.22 104.562±33.69 185.913±66.94 178.324±10.09 87.431±7.92 102.662±3.12 58.148±18.52 280.878±23.42 24.639±2.82 187.246±44.49 168.736±64.21 29.433±11.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00010B CIL_00010B_0003 CGP 9:107614138-107668968

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000186 IEA activation of MAPKK activity
GO:0001664 IBA G-protein coupled receptor binding
GO:0001973 IBA adenosine receptor signaling pathway
GO:0003924 IBA GTPase activity
GO:0004871 IBA signal transducer activity
GO:0005515 IPI protein binding
GO:0005525 ISA GTP binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0005813 ISS centrosome
GO:0005829 IEA cytosol
GO:0005834 IBA heterotrimeric G-protein complex
GO:0005886 ISS plasma membrane
GO:0006184 IEA GTP catabolic process
GO:0007049 IEA cell cycle
GO:0007193 ISA adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
GO:0007213 IMP G-protein coupled acetylcholine receptor signaling pathway
GO:0007214 IBA gamma-aminobutyric acid signaling pathway
GO:0008283 IPI cell proliferation
GO:0008284 IEA positive regulation of cell proliferation
GO:0016020 IEA membrane
GO:0030496 ISS midbody
GO:0031683 IBA G-protein beta/gamma-subunit complex binding
GO:0031982 IEA vesicle
GO:0035556 IEA intracellular signal transduction
GO:0045121 IEA membrane raft
GO:0046872 IEA metal ion binding
GO:0050805 IEA negative regulation of synaptic transmission
GO:0051301 ISS cell division
GO:0051924 IEA regulation of calcium ion transport
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000154429 gnai2b-001 protein_coding Danio_rerio 0 952
ENSDART00000024181 gnai2b-201 protein_coding Danio_rerio 0 832
ENSDART00000079694 gnai2b-202 protein_coding Danio_rerio 0 830
ENSDART00000128070 gnai2a-001 protein_coding Danio_rerio 0 822
ENSDART00000046298 gnaia-201 protein_coding Danio_rerio 0 682
ENSDART00000138985 gnaia-001 protein_coding Danio_rerio 0 682
ENSDART00000047528 gnai3-001 protein_coding Danio_rerio 0 671
ENSDART00000036531 gnai1-001 protein_coding Danio_rerio 0 664
ENSDART00000052346 gnao1b-001 protein_coding Danio_rerio 2e-38 165
ENST00000078429 GNA11-001 protein_coding Homo_sapiens 4e-27 128
ENST00000232461 GNAT1-001 protein_coding Homo_sapiens 0 318
ENST00000262493 GNAO1-001 protein_coding Homo_sapiens 0 294
ENST00000262494 GNAO1-002 protein_coding Homo_sapiens 0 359
ENST00000266027 GNAI2-201 protein_coding Homo_sapiens 0 2200
ENST00000313601 GNAI2-001 protein_coding Homo_sapiens 0 2606
ENST00000422163 GNAI2-003 protein_coding Homo_sapiens 0 1757
ENST00000433068 GNAT1-002 protein_coding Homo_sapiens 0 318
ENST00000440628 GNAI2-009 protein_coding Homo_sapiens 0 1618
ENST00000440836 GNAT1-003 protein_coding Homo_sapiens 0.000000000000003 86
ENST00000441156 GNAI2-005 nonsense_mediated_decay Homo_sapiens 0 2143
ENST00000446079 GNAI2-004 nonsense_mediated_decay Homo_sapiens 0 1759
ENST00000451956 GNAI2-002 protein_coding Homo_sapiens 0 1580
ENST00000490122 GNAI2-006 retained_intron Homo_sapiens 0 1681
ENST00000491100 GNAI2-007 processed_transcript Homo_sapiens 0 2211
ENST00000492383 GNAI2-011 retained_intron Homo_sapiens 0 793
ENST00000541815 GNAI2P1-001 processed_pseudogene Homo_sapiens 0 396
ENST00000563661 GNAO1-004 retained_intron Homo_sapiens 5e-24 115
ENST00000586180 GNA11-004 processed_transcript Homo_sapiens 2e-23 113
ENST00000587636 GNA11-007 protein_coding Homo_sapiens 1e-26 124
ENST00000590534 GNA11-002 retained_intron Homo_sapiens 0.0000000001 73
ENST00000591301 GNA11-006 retained_intron Homo_sapiens 8e-25 117

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