C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: FERM, RhoGEF and pleckstrin domain protein 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000120301 Farp2-001 ENSMUSG00000034066 10090 + 1:93512079-93621976 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; KidneyLiverPlacentaENSMUST00000120301
Transcript ID Kidney Liver Placenta
ENSMUST00000120301 5.347±0.00 4.475±0.77 11.292±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002JL CIL_0002JL_0002 CGP 1:93478964-93621976
CIL_0004UB CIL_0004UB_0003 CGP 1:93512079-93658659

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 ISO Rho guanyl-nucleotide exchange factor activity
GO:0005737 ISO cytoplasm
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0007155 IMP cell adhesion
GO:0008092 IEA cytoskeletal protein binding
GO:0016322 ISO neuron remodeling
GO:0016601 ISO Rac protein signal transduction
GO:0019898 IEA extrinsic component of membrane
GO:0030316 IMP osteoclast differentiation
GO:0030676 IDA Rac guanyl-nucleotide exchange factor activity
GO:0031532 IMP actin cytoskeleton reorganization
GO:0032321 ISO positive regulation of Rho GTPase activity
GO:0032855 IDA positive regulation of Rac GTPase activity
GO:0033623 IMP regulation of integrin activation
GO:0071526 IMP semaphorin-plexin signaling pathway
GO:0071800 IMP podosome assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264042 FARP2-001 protein_coding Homo_sapiens 0 2933
ENST00000316586 STK25-001 protein_coding Homo_sapiens 0 219
ENST00000373287 FARP2-002 protein_coding Homo_sapiens 0 1694
ENST00000412332 FARP2-022 protein_coding Homo_sapiens 2e-32 143
ENST00000413432 FARP2-014 protein_coding Homo_sapiens 0 364
ENST00000418082 FARP2-007 protein_coding Homo_sapiens 0 375
ENST00000422951 FARP2-017 protein_coding Homo_sapiens 0 228
ENST00000470617 FARP2-003 retained_intron Homo_sapiens 0 701
ENST00000472181 STK25-034 processed_transcript Homo_sapiens 4e-19 99
ENST00000473082 FARP2-010 processed_transcript Homo_sapiens 0 224
ENST00000478489 FARP2-004 processed_transcript Homo_sapiens 0 235
ENST00000491425 FARP2-019 processed_transcript Homo_sapiens 0 305

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