C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phospholipase C, gamma 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034330 Plcg2 10090 + 8:117498291-117635140 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000081232 Plcg2-201 117498291-117635140 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000081232
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000081232 1.669±0.59 2.504±0.46 3.808±0.26 0.536±0.32 8.674±3.91 3.013±0.55 1.394±0.46 4.193±1.08 2.151±1.81 5.771±0.17 0.349±0.33 2.935±0.89 4.642±2.76 1.698±1.76

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003A9 CIL_0003A9_0002 CGP 8:117257019-117635140
CIL_0001Z3 CIL_0001Z3_0002 CGP 8:117498291-117673689

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002316 IMP follicular B cell differentiation
GO:0004435 ISS phosphatidylinositol phospholipase C activity
GO:0004629 TAS phospholipase C activity
GO:0004871 IEA signal transducer activity
GO:0005515 IPI protein binding
GO:0005829 IMP cytosol
GO:0005886 ISS plasma membrane
GO:0006661 ISS phosphatidylinositol biosynthetic process
GO:0009395 IEA phospholipid catabolic process
GO:0010468 IMP regulation of gene expression
GO:0030183 IMP B cell differentiation
GO:0032237 IMP activation of store-operated calcium channel activity
GO:0032496 IDA response to lipopolysaccharide
GO:0032959 IDA inositol trisphosphate biosynthetic process
GO:0035556 IEA intracellular signal transduction
GO:0043069 IMP negative regulation of programmed cell death
GO:0050852 IDA T cell receptor signaling pathway
GO:0050853 IMP B cell receptor signaling pathway
GO:0051209 IMP release of sequestered calcium ion into cytosol
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068763 plcg2 phospholipase C, gamma 2 protein_coding Danio_rerio
ENSG00000197943 PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) protein_coding Homo_sapiens

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