C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: egl-9 family hypoxia-inducible factor 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035105 Egln3 10090 - 12:54178981-54203860 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000039516 Egln3-001 54178981-54203860 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000039516
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000039516 2.628±0.22 2.422±0.96 17.352±3.53 2.430±0.45 3.631±1.93 14.273±1.35 18.729±5.58 3.435±0.08 7.004±6.03 3.098±1.85 9.294±1.55 3.038±1.37 2.278±0.45 0.222±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007M4 CIL_0007M4_0002 UCNEbase 12:52937233-54554218
CIL_0005RA CIL_0005RA_0003 CGP 12:53248677-54203860
CIL_0008MA CIL_0008MA_0002 VISTA 12:53626314-54227018
CIL_0008M9 CIL_0008M9_0002 VISTA 12:53700471-54301518
CIL_0009C2 CIL_0009C2_0002 VISTA 12:53861494-54463193
CIL_0005R9 CIL_0005R9_0003 CGP 12:54178981-54656572

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0005506 IEA iron ion binding
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006915 ISS apoptotic process
GO:0006919 ISS activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0006974 IEA cellular response to DNA damage stimulus
GO:0018126 ISS protein hydroxylation
GO:0018401 IEA peptidyl-proline hydroxylation to 4-hydroxy-L-proline
GO:0031418 IEA L-ascorbic acid binding
GO:0031545 IEA peptidyl-proline 4-dioxygenase activity
GO:0042127 IMP regulation of cell proliferation
GO:0043523 IMP regulation of neuron apoptotic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032553 egln3 egl nine homolog 3 (C. elegans) protein_coding Danio_rerio
ENSG00000129521 EGLN3 egl-9 family hypoxia-inducible factor 3 protein_coding Homo_sapiens

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