C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heparanase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035273 Hpse 10090 - 5:100679484-100719716 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000045617 Hpse-001 100679484-100719716 protein_coding
  ENSMUST00000112908 Hpse-002 100684581-100719705 protein_coding

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000045617ENSMUST00000112908
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000045617 2.091±0.42 0.276±0.13 4.745±0.19 0.155±0.06 3.537±0.87 4.436±0.98 0.491±0.16 0.415±0.24 1.249±0.41 1.555±0.58 0.205±0.13 0.716±0.34 2.421±1.17 1.256±0.53
ENSMUST00000112908 0.862±0.15 0.555±0.37 N/A 0.110±0.00 5.706±4.22 7.238±1.15 N/A 0.152±0.00 0.274±0.08 2.352±0.04 N/A 1.886±0.66 N/A 0.113±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00069P CIL_00069P_0002 CGP 5:100654723-100719716
CIL_0006JB CIL_0006JB_0002 CGP 5:100679484-100798598

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005578 TAS proteinaceous extracellular matrix
GO:0005634 IDA nucleus
GO:0005764 IEA lysosome
GO:0005975 IEA carbohydrate metabolic process
GO:0007160 IEA cell-matrix adhesion
GO:0010575 IEA positive regulation vascular endothelial growth factor production
GO:0016020 IEA membrane
GO:0030194 IEA positive regulation of blood coagulation
GO:0030200 ISS heparan sulfate proteoglycan catabolic process
GO:0030305 ISO:ISS heparanase activity
GO:0033690 IDA positive regulation of osteoblast proliferation
GO:0042060 IDA wound healing
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045121 IDA membrane raft
GO:0045545 IEA syndecan binding
GO:0046983 IEA protein dimerization activity
GO:0051797 IEA regulation of hair follicle development
GO:0051798 IDA positive regulation of hair follicle development
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0060055 IDA angiogenesis involved in wound healing
GO:0061042 IDA vascular wound healing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063634 hpse heparanase protein_coding Danio_rerio
ENSG00000173083 HPSE heparanase protein_coding Homo_sapiens

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