C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adrenergic receptor, beta 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035283 Adrb1 10090 + 19:56722372-56724862 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038949 Adrb1-201 56722372-56724862 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000038949
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000038949 2.492±0.95 4.193±1.01 0.647±0.07 4.235±4.66 4.057±2.49 3.581±0.61 8.796±1.97 1.645±0.24 0.388±0.17 37.256±12.11 0.054±0.03 1.498±0.62 8.687±8.28 1.631±0.69

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001R7 CIL_0001R7_0003 CGP 19:56548261-56724862
CIL_0006OP CIL_0006OP_0002 CGP 19:56722372-56822190

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001996 IMP positive regulation of heart rate by epinephrine-norepinephrine
GO:0001997 IDA positive regulation of the force of heart contraction by epinephrine-norepinephrine
GO:0002024 IGI diet induced thermogenesis
GO:0002025 IGI vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0003061 IEA positive regulation of the force of heart contraction by norepinephrine
GO:0003084 IEA positive regulation of systemic arterial blood pressure
GO:0004940 IDA beta1-adrenergic receptor activity
GO:0005057 ISS receptor signaling protein activity
GO:0005088 ISS Ras guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005769 ISS early endosome
GO:0005886 ISS plasma membrane
GO:0005980 IEA glycogen catabolic process
GO:0006915 IEA apoptotic process
GO:0007189 IMP adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007266 IEA Rho protein signal transduction
GO:0007568 IEA aging
GO:0007613 IEA memory
GO:0008144 IEA drug binding
GO:0009409 IGI response to cold
GO:0010460 IEA positive regulation of heart rate
GO:0016020 IMP membrane
GO:0016021 IEA integral component of membrane
GO:0019233 IEA sensory perception of pain
GO:0030165 IEA PDZ domain binding
GO:0030819 ISS positive regulation of cAMP biosynthetic process
GO:0031649 IGI heat generation
GO:0031694 IEA alpha-2A adrenergic receptor binding
GO:0032320 ISS positive regulation of Ras GTPase activity
GO:0033365 IEA protein localization to organelle
GO:0035240 IEA dopamine binding
GO:0035811 IEA negative regulation of urine volume
GO:0040015 IGI negative regulation of multicellular organism growth
GO:0042060 IEA wound healing
GO:0042596 IMP fear response
GO:0043065 IEA positive regulation of apoptotic process
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0043950 ISS positive regulation of cAMP-mediated signaling
GO:0045986 IEA negative regulation of smooth muscle contraction
GO:0046878 IEA positive regulation of saliva secretion
GO:0046982 IEA protein heterodimerization activity
GO:0050873 IGI brown fat cell differentiation
GO:0051379 IEA epinephrine binding
GO:0051380 IEA norepinephrine binding
GO:0051924 IEA regulation of calcium ion transport
GO:0055088 IEA lipid homeostasis
GO:0060080 IEA regulation of inhibitory postsynaptic membrane potential
GO:0061051 IEA positive regulation of cell growth involved in cardiac muscle cell development
GO:0071880 ISS adenylate cyclase-activating adrenergic receptor signaling pathway
GO:0086004 IEA regulation of cardiac muscle cell contraction
GO:1900135 IEA positive regulation of renin secretion into blood stream
GO:2001259 IEA positive regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007490 adrb1 adrenergic receptor, beta 1 protein_coding Danio_rerio
ENSDARG00000088851 adrb1 adrenergic receptor, beta 1 protein_coding Danio_rerio
ENSG00000043591 ADRB1 adrenoceptor beta 1 protein_coding Homo_sapiens

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