C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: forkhead box A1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035451 Foxa1 10090 - 12:57540631-57546121 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000044380 Foxa1-201 57540631-57546121 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000044380
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000044380 0.155±0.00 0.014±0.00 42.133±10.68 0.726±0.53 6.789±2.85 10.461±1.32 0.247±0.19 0.344±0.11 2.938±1.49 6.294±1.37 0.016±0.00 0.035±0.03 0.512±0.56 0.093±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00092Q CIL_00092Q_0002 VISTA 12:56991377-57592384
CIL_0005R8 CIL_0005R8_0003 CGP 12:57230427-57546121

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0005902 IDA microvillus
GO:0006338 IDA chromatin remodeling
GO:0006351 IEA transcription, DNA-templated
GO:0008134 IEA transcription factor binding
GO:0010468 IGI regulation of gene expression
GO:0010719 IEA negative regulation of epithelial to mesenchymal transition
GO:0019904 IEA protein domain specific binding
GO:0021904 IGI dorsal/ventral neural tube patterning
GO:0030324 IGI lung development
GO:0032355 IEA response to estradiol
GO:0033148 IEA positive regulation of intracellular estrogen receptor signaling pathway
GO:0035239 IMP tube morphogenesis
GO:0042445 IMP hormone metabolic process
GO:0042593 IMP glucose homeostasis
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045666 IGI positive regulation of neuron differentiation
GO:0045880 IGI positive regulation of smoothened signaling pathway
GO:0045931 IEA positive regulation of mitotic cell cycle
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048646 IGI anatomical structure formation involved in morphogenesis
GO:0048665 IGI neuron fate specification
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051726 IDA regulation of cell cycle
GO:0060441 IGI epithelial tube branching involved in lung morphogenesis
GO:0060487 IGI lung epithelial cell differentiation
GO:0060528 IMP secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0060738 IGI epithelial-mesenchymal signaling involved in prostate gland development
GO:0060740 IMP prostate gland epithelium morphogenesis
GO:0060741 IMP prostate gland stromal morphogenesis
GO:0060743 IMP epithelial cell maturation involved in prostate gland development
GO:0061448 IGI connective tissue development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019150 foxa1 forkhead box A1 protein_coding Danio_rerio
ENSG00000129514 FOXA1 forkhead box A1 protein_coding Homo_sapiens

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