C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: forkhead box A1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000129514 FOXA1 9606 - 14:37589984-37596059 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000250448 FOXA1-001 37589984-37595034 protein_coding
  ENST00000545425 FOXA1-002 37591093-37594262 processed_transcript
  ENST00000553751 FOXA1-003 37592516-37595110 nonsense_mediated_decay
  ENST00000554607 FOXA1-004 37593875-37594950 processed_transcript
  ENST00000557418 FOXA1-005 37595024-37596059 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryENST00000250448ENST00000545425
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary
ENST00000250448 0.046±0.00 N/A 0.022±0.00 0.043±0.00 1.527±0.00 1.748±0.00 0.897±0.66 7.158±5.63 3.086±2.42 1.636±1.51
ENST00000545425 0.031±0.00 0.057±0.00 N/A N/A N/A N/A 0.340±0.00 N/A N/A 0.792±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005R8 CIL_0005R8_0002 CGP 14:37197913-37596059
CIL_0005R7 CIL_0005R7_0002 CGP 14:37589984-38041442

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001077 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 TAS:IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IDA nucleus
GO:0005902 IEA microvillus
GO:0006338 ISS chromatin remodeling
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0008134 IEA transcription factor binding
GO:0010468 IEA regulation of gene expression
GO:0010719 IMP negative regulation of epithelial to mesenchymal transition
GO:0019904 IEA protein domain specific binding
GO:0021904 IEA dorsal/ventral neural tube patterning
GO:0030324 IEA lung development
GO:0032355 IDA response to estradiol
GO:0033148 IMP positive regulation of intracellular estrogen receptor signaling pathway
GO:0035239 IEA tube morphogenesis
GO:0042445 IEA hormone metabolic process
GO:0042593 IEA glucose homeostasis
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045880 IEA positive regulation of smoothened signaling pathway
GO:0045931 IMP positive regulation of mitotic cell cycle
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048646 IEA anatomical structure formation involved in morphogenesis
GO:0048665 IEA neuron fate specification
GO:0051091 IMP positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051726 IEA regulation of cell cycle
GO:0060441 IEA epithelial tube branching involved in lung morphogenesis
GO:0060487 IEA lung epithelial cell differentiation
GO:0060528 IEA secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0060738 IEA epithelial-mesenchymal signaling involved in prostate gland development
GO:0060740 IEA prostate gland epithelium morphogenesis
GO:0060741 IEA prostate gland stromal morphogenesis
GO:0060743 IEA epithelial cell maturation involved in prostate gland development
GO:0061448 IEA connective tissue development
GO:2000049 IC positive regulation of cell-cell adhesion mediated by cadherin

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019150 foxa1 forkhead box A1 protein_coding Danio_rerio
ENSMUSG00000035451 Foxa1 forkhead box A1 protein_coding Mus_musculus

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