C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: inhibitor of Bruton agammaglobulinemia tyrosine kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035941 Ibtk 10090 - 9:85687360-85749334 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000039213 Ibtk-001 85687360-85749334 protein_coding
  ENSMUST00000185353 Ibtk-005 85720183-85749314 retained_intron
  ENSMUST00000186322 Ibtk-002 85687557-85720823 retained_intron
  ENSMUST00000186447 Ibtk-006 85728293-85731235 retained_intron
  ENSMUST00000187521 Ibtk-003 85687542-85749334 nonsense_mediated_decay
  ENSMUST00000188768 Ibtk-007 85708168-85718538 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000039213ENSMUST00000185353ENSMUST00000186322ENSMUST00000187521
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000039213 2.650±1.44 3.050±1.44 7.709±1.32 3.903±1.53 2.543±1.13 3.663±1.01 3.286±0.38 2.941±0.67 4.806±1.41 3.580±0.64 9.374±1.35 5.790±4.80 4.851±1.63 2.053±0.18
ENSMUST00000185353 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.295±0.00 N/A N/A
ENSMUST00000186322 N/A N/A N/A 1.068±0.06 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000187521 1.153±0.57 3.629±1.34 1.937±0.00 1.262±0.18 1.380±0.62 2.165±1.18 0.614±0.00 1.167±0.28 1.472±0.62 1.376±0.00 2.683±0.58 6.297±3.31 2.620±1.20 0.908±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006G7 CIL_0006G7_0002 CGP 9:85320439-85749334
CIL_0006GF CIL_0006GF_0002 CGP 9:85687360-85847040

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0016020 IEA membrane
GO:0019901 IEA protein kinase binding
GO:0030292 IEA protein tyrosine kinase inhibitor activity
GO:0051209 IEA release of sequestered calcium ion into cytosol
GO:0061099 IEA negative regulation of protein tyrosine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074424 ibtk inhibitor of Bruton agammaglobulinemia tyrosine kinase protein_coding Danio_rerio
ENSG00000005700 IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase protein_coding Homo_sapiens

Loading