C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: dedicator of cytokinesis 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000037488 Dock4-201 ENSMUSG00000035954 10090 + 12:40446053-40846486 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000037488
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000037488 3.409±0.56 4.219±0.81 2.009±0.20 10.405±0.55 1.709±0.74 0.770±0.33 1.467±0.92 2.375±0.59 1.892±1.71 15.950±1.89 1.195±0.31 8.321±2.76 0.539±0.44 0.248±0.07

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005829 ISS cytosol
GO:0007264 IEA small GTPase mediated signal transduction
GO:0016020 ISS membrane
GO:0017124 IEA SH3 domain binding
GO:0030165 IEA PDZ domain binding
GO:0030675 IEA Rac GTPase activator activity
GO:0030971 IEA receptor tyrosine kinase binding
GO:0032420 IDA stereocilium
GO:0032421 IDA stereocilium bundle
GO:0032855 IEA positive regulation of Rac GTPase activity
GO:0048365 IEA Rac GTPase binding
GO:0060326 ISS cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000036646 dock4b-201 protein_coding Danio_rerio 0 1103
ENSDART00000136355 dock4b-001 protein_coding Danio_rerio 0 202
ENST00000417165 DOCK4-010 protein_coding Homo_sapiens 0 536
ENST00000423057 DOCK4-007 protein_coding Homo_sapiens 0 5018
ENST00000428053 DOCK4-014 nonsense_mediated_decay Homo_sapiens 0 765
ENST00000428084 DOCK4-005 protein_coding Homo_sapiens 0 8556
ENST00000437129 DOCK4-013 protein_coding Homo_sapiens 0 791
ENST00000437633 DOCK4-001 protein_coding Homo_sapiens 0 4680
ENST00000445943 DOCK4-004 protein_coding Homo_sapiens 0 4287
ENST00000450156 DOCK4-012 protein_coding Homo_sapiens 0 789
ENST00000464338 DOCK4-011 retained_intron Homo_sapiens 0 294
ENST00000468571 DOCK4-003 processed_transcript Homo_sapiens 0 918
ENST00000469898 DOCK4-017 retained_intron Homo_sapiens 0 765
ENST00000476846 DOCK4-002 processed_transcript Homo_sapiens 0 3430
ENST00000486186 DOCK4-015 retained_intron Homo_sapiens 0 1471
ENST00000492436 DOCK4-009 processed_transcript Homo_sapiens 0 632
ENST00000492532 DOCK4-008 processed_transcript Homo_sapiens 0 379
ENST00000494651 DOCK4-201 protein_coding Homo_sapiens 0 4180

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