C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: growth arrest and DNA-damage-inducible 45 alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000043098 Gadd45a-001 ENSMUSG00000036390 10090 - 6:67035096-67037406 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000043098
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000043098 7.399±0.92 7.520±3.25 25.820±6.13 3.048±0.73 3.913±1.67 9.983±0.67 4.587±1.19 10.017±2.32 24.521±26.45 4.412±0.42 11.321±1.50 27.350±17.70 11.649±1.78 0.777±0.49

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000185 IEA activation of MAPKKK activity
GO:0001047 IDA core promoter binding
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0005737 IEA cytoplasm
GO:0006469 IDA negative regulation of protein kinase activity
GO:0007050 IEA cell cycle arrest
GO:0007098 IGI centrosome cycle
GO:0042770 IEA signal transduction in response to DNA damage
GO:0043065 IEA positive regulation of apoptotic process
GO:0046330 IEA positive regulation of JNK cascade
GO:0051726 IDA regulation of cell cycle
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071479 IEA cellular response to ionizing radiation
GO:1900745 IEA positive regulation of p38MAPK cascade
GO:2000379 IEA positive regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000063996 gadd45aa-001 protein_coding Danio_rerio 1e-32 145
ENST00000370985 GADD45A-003 protein_coding Homo_sapiens 0 638
ENST00000370986 GADD45A-001 protein_coding Homo_sapiens 0 1055
ENST00000460575 GADD45A-002 processed_transcript Homo_sapiens 0 289
ENST00000484245 GADD45A-004 processed_transcript Homo_sapiens 0 409
ENST00000617962 GADD45A-201 protein_coding Homo_sapiens 0 562

Loading