C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hypoxia-inducible factor 1, alpha subunit inhibitor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000036450 Hif1an 10090 + 19:44562850-44576274 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000040455 Hif1an-001 44562850-44576274 protein_coding
  ENSMUST00000131032 Hif1an-002 44562850-44563952 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000040455
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000040455 8.670±4.29 8.410±1.19 6.297±0.62 7.057±3.31 12.540±5.30 11.945±1.66 7.458±1.29 8.573±0.37 5.307±1.89 14.135±1.95 42.374±4.96 13.088±3.38 10.112±3.75 9.106±2.58

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007QB CIL_0007QB_0002 VISTA 19:44214132-44815870
CIL_00082U CIL_00082U_0002 VISTA 19:44330970-44933041
CIL_00082V CIL_00082V_0002 VISTA 19:44333644-44934226
CIL_00093R CIL_00093R_0002 VISTA 19:44370805-44971431
CIL_00093O CIL_00093O_0002 VISTA 19:44374626-44975238
CIL_0008BC CIL_0008BC_0002 VISTA 19:44398597-45000718
CIL_0008BD CIL_0008BD_0002 VISTA 19:44496521-45098014
CIL_0007U1 CIL_0007U1_0002 VISTA 19:44501251-45102539
CIL_0005DQ CIL_0005DQ_0002 CGP 19:44548572-44576274
CIL_0005DR CIL_0005DR_0002 CGP 19:44562850-44837871

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005112 ISS Notch binding
GO:0005506 IEA iron ion binding
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IEA zinc ion binding
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0031406 IEA carboxylic acid binding
GO:0036138 ISS peptidyl-histidine hydroxylation
GO:0036139 ISS peptidyl-histidine dioxygenase activity
GO:0036140 ISS peptidyl-asparagine 3-dioxygenase activity
GO:0042264 ISS peptidyl-aspartic acid hydroxylation
GO:0042265 ISS peptidyl-asparagine hydroxylation
GO:0042803 IEA protein homodimerization activity
GO:0045663 ISS positive regulation of myoblast differentiation
GO:0045746 ISS negative regulation of Notch signaling pathway
GO:0048037 IEA cofactor binding
GO:0048471 IEA perinuclear region of cytoplasm
GO:0051059 IEA NF-kappaB binding
GO:0055114 ISS oxidation-reduction process
GO:0061428 ISS negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071532 ISS ankyrin repeat binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031915 hif1an hypoxia-inducible factor 1, alpha subunit inhibitor protein_coding Danio_rerio
ENSG00000166135 HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor protein_coding Homo_sapiens

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