C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fibroblast growth factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037225 Fgf2 10090 + 3:37312519-37405377 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000038885 Fgf2-007 37348653-37404889 protein_coding
  ENSMUST00000091203 Fgf2-005 37380755-37404797 protein_coding
  ENSMUST00000108120 Fgf2-004 37380755-37404797 protein_coding
  ENSMUST00000138563 Fgf2-001 37348346-37405377 protein_coding
  ENSMUST00000138710 Fgf2-006 37312519-37404866 processed_transcript
  ENSMUST00000145228 Fgf2-003 37380659-37404797 processed_transcript
  ENSMUST00000150021 Fgf2-002 37366990-37404797 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBreastColonLungOvaryENSMUST00000038885
Transcript ID Adrenal Breast Colon Lung Ovary
ENSMUST00000038885 5.548±0.00 11.210±1.70 2.244±0.40 6.387±1.01 5.571±1.49

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 IDA activation of MAPKK activity
GO:0001525 IDA angiogenesis
GO:0001658 ISS branching involved in ureteric bud morphogenesis
GO:0001759 IDA organ induction
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0001938 IDA positive regulation of endothelial cell proliferation
GO:0005104 IPI fibroblast growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0007568 IEA aging
GO:0008083 IDA growth factor activity
GO:0008201 IEA heparin binding
GO:0008284 IGI positive regulation of cell proliferation
GO:0008285 IGI negative regulation of cell proliferation
GO:0008543 IGI fibroblast growth factor receptor signaling pathway
GO:0009792 IEA embryo development ending in birth or egg hatching
GO:0010001 IMP glial cell differentiation
GO:0010595 IDA positive regulation of endothelial cell migration
GO:0010628 IDA positive regulation of gene expression
GO:0021762 IMP substantia nigra development
GO:0021940 IDA positive regulation of cerebellar granule cell precursor proliferation
GO:0030324 IDA lung development
GO:0042060 IEA wound healing
GO:0042660 ISO positive regulation of cell fate specification
GO:0045597 IDA positive regulation of cell differentiation
GO:0045669 IGI positive regulation of osteoblast differentiation
GO:0045766 IGI positive regulation of angiogenesis
GO:0045893 TAS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046668 IDA regulation of retinal cell programmed cell death
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0048678 IMP response to axon injury
GO:0048864 IMP stem cell development
GO:0050679 IDA positive regulation of epithelial cell proliferation
GO:0051726 IDA regulation of cell cycle
GO:0051781 IEA positive regulation of cell division
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0060038 TAS cardiac muscle cell proliferation
GO:0060045 IEA positive regulation of cardiac muscle cell proliferation
GO:0060128 IDA corticotropin hormone secreting cell differentiation
GO:0060129 IDA thyroid-stimulating hormone-secreting cell differentiation
GO:0060548 ISS negative regulation of cell death
GO:0060644 IDA mammary gland epithelial cell differentiation
GO:0060978 IEA angiogenesis involved in coronary vascular morphogenesis
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0090263 IDA positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075031 fgf2 fibroblast growth factor 2 protein_coding Danio_rerio
ENSG00000138685 FGF2 fibroblast growth factor 2 (basic) protein_coding Homo_sapiens

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