C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fibroblast growth factor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000138563 Fgf2-001 ENSMUSG00000037225 10090 + 3:37348346-37405377 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000186 IDA activation of MAPKK activity
GO:0001525 IDA angiogenesis
GO:0001658 ISS branching involved in ureteric bud morphogenesis
GO:0001759 IDA organ induction
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0001938 IDA positive regulation of endothelial cell proliferation
GO:0005104 IPI fibroblast growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0007568 IEA aging
GO:0008083 IDA growth factor activity
GO:0008201 IEA heparin binding
GO:0008284 IGI positive regulation of cell proliferation
GO:0008285 IGI negative regulation of cell proliferation
GO:0008543 IGI fibroblast growth factor receptor signaling pathway
GO:0009792 IEA embryo development ending in birth or egg hatching
GO:0010001 IMP glial cell differentiation
GO:0010595 IDA positive regulation of endothelial cell migration
GO:0010628 IDA positive regulation of gene expression
GO:0021762 IMP substantia nigra development
GO:0021940 IDA positive regulation of cerebellar granule cell precursor proliferation
GO:0030324 IDA lung development
GO:0042060 IEA wound healing
GO:0042660 ISO positive regulation of cell fate specification
GO:0045597 IDA positive regulation of cell differentiation
GO:0045669 IGI positive regulation of osteoblast differentiation
GO:0045766 IGI positive regulation of angiogenesis
GO:0045893 TAS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046668 IDA regulation of retinal cell programmed cell death
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0048678 IMP response to axon injury
GO:0048864 IMP stem cell development
GO:0050679 IDA positive regulation of epithelial cell proliferation
GO:0051726 IDA regulation of cell cycle
GO:0051781 IEA positive regulation of cell division
GO:0051897 IDA positive regulation of protein kinase B signaling
GO:0060038 TAS cardiac muscle cell proliferation
GO:0060045 IEA positive regulation of cardiac muscle cell proliferation
GO:0060128 IDA corticotropin hormone secreting cell differentiation
GO:0060129 IDA thyroid-stimulating hormone-secreting cell differentiation
GO:0060548 ISS negative regulation of cell death
GO:0060644 IDA mammary gland epithelial cell differentiation
GO:0060978 IEA angiogenesis involved in coronary vascular morphogenesis
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:0090263 IDA positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264498 FGF2-001 protein_coding Homo_sapiens 0 599
ENST00000608478 FGF2-002 protein_coding Homo_sapiens 0 599
ENST00000614010 FGF2-201 protein_coding Homo_sapiens 0 599

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