C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitogen-activated protein kinase kinase kinase kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037337 Map4k1 10090 + 7:28982854-29003279 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000085835 Map4k1-201 28982854-29003279 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000085835
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000085835 2.150±0.17 0.465±0.20 1.203±0.04 1.469±0.80 13.749±6.89 1.798±0.64 0.611±0.34 0.970±0.53 3.046±2.66 4.446±0.43 0.367±0.49 1.154±0.49 1.015±0.38 4.354±2.51

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IPI protein binding
GO:0005524 IDA ATP binding
GO:0006468 IDA protein phosphorylation
GO:0006950 IEA response to stress
GO:0008283 ISS cell proliferation
GO:0008349 IEA MAP kinase kinase kinase kinase activity
GO:0016020 IEA membrane
GO:0018105 ISS peptidyl-serine phosphorylation
GO:0035556 IDA intracellular signal transduction
GO:0046777 ISS protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088216 MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 protein_coding Danio_rerio
ENSG00000104814 MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 protein_coding Homo_sapiens

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