C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase kinase kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000085835 Map4k1-201 ENSMUSG00000037337 10090 + 7:28982854-29003279 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000085835
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000085835 2.150±0.17 0.465±0.20 1.203±0.04 1.469±0.80 13.749±6.89 1.798±0.64 0.611±0.34 0.970±0.53 3.046±2.66 4.446±0.43 0.367±0.49 1.154±0.49 1.015±0.38 4.354±2.51

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005083 IEA small GTPase regulator activity
GO:0005515 IPI protein binding
GO:0005524 IDA ATP binding
GO:0006468 IDA protein phosphorylation
GO:0006950 IEA response to stress
GO:0008283 ISS cell proliferation
GO:0008349 IEA MAP kinase kinase kinase kinase activity
GO:0016020 IEA membrane
GO:0018105 ISS peptidyl-serine phosphorylation
GO:0035556 IDA intracellular signal transduction
GO:0046777 ISS protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000396857 MAP4K1-001 protein_coding Homo_sapiens 0 2453
ENST00000585583 MAP4K1-005 nonsense_mediated_decay Homo_sapiens 0 553
ENST00000586296 MAP4K1-004 protein_coding Homo_sapiens 0 1194
ENST00000587300 MAP4K1-007 retained_intron Homo_sapiens 0 412
ENST00000588083 MAP4K1-008 retained_intron Homo_sapiens 0 442
ENST00000589130 MAP4K1-003 protein_coding Homo_sapiens 0 2398
ENST00000591210 MAP4K1-015 retained_intron Homo_sapiens 2e-38 161
ENST00000591517 MAP4K1-002 protein_coding Homo_sapiens 0 2335
ENST00000591921 MAP4K1-006 protein_coding Homo_sapiens 0 1253
ENST00000593196 MAP4K1-014 processed_transcript Homo_sapiens 1e-24 117

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