C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histocompatibility 2, class II, locus DMa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037649 H2-DMa 10090 + 17:34135182-34139101 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000042121 H2-DMa-001 34135182-34139101 protein_coding
  ENSMUST00000173907 H2-DMa-002 34137028-34138180 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000042121ENSMUST00000173907
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000042121 6.364±1.80 4.682±1.10 8.973±0.32 3.015±1.21 32.402±6.17 7.423±1.17 2.144±1.00 8.077±2.16 1.246±0.65 32.023±8.59 0.643±0.41 5.626±2.87 0.938±0.60 4.432±1.85
ENSMUST00000173907 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.422±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002503 IEA peptide antigen assembly with MHC class II protein complex
GO:0005515 IPI protein binding
GO:0005622 IDA intracellular
GO:0005764 IDA lysosome
GO:0005765 IDA lysosomal membrane
GO:0005770 IDA late endosome
GO:0005771 IDA multivesicular body
GO:0006461 IDA protein complex assembly
GO:0009986 IEA cell surface
GO:0010008 IDA endosome membrane
GO:0015031 IDA protein transport
GO:0016021 IEA integral component of membrane
GO:0016064 IMP immunoglobulin mediated immune response
GO:0019882 IDA antigen processing and presentation
GO:0019886 IDA antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0023026 IEA MHC class II protein complex binding
GO:0042613 IEA MHC class II protein complex
GO:0045059 IMP positive thymic T cell selection
GO:0045582 IMP positive regulation of T cell differentiation
GO:0048839 IDA inner ear development
GO:0050778 IMP positive regulation of immune response
GO:0051085 IDA chaperone mediated protein folding requiring cofactor
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000204257 HLA-DMA major histocompatibility complex, class II, DM alpha protein_coding Homo_sapiens

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