C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: major histocompatibility complex, class II, DM alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204257 HLA-DMA 9606 - 6:32948613-32969094 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374843 HLA-DMA-001 32948613-32953122 protein_coding
  ENST00000395303 HLA-DMA-002 32948613-32953108 protein_coding
  ENST00000395305 HLA-DMA-004 32948613-32953061 protein_coding
  ENST00000422832 HLA-DMA-009 32949657-32969094 protein_coding
  ENST00000456800 HLA-DMA-006 32949271-32952461 protein_coding
  ENST00000464392 HLA-DMA-010 32948771-32968444 processed_transcript
  ENST00000475627 HLA-DMA-005 32950084-32953034 retained_intron
  ENST00000477541 HLA-DMA-003 32948613-32953108 retained_intron
  ENST00000480785 HLA-DMA-007 32948613-32949671 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastHeartKidneyLungPlacentaENST00000374843
Transcript ID Adipose Adrenal Breast Heart Kidney Lung Placenta
ENST00000374843 40.926±0.00 208.484±0.00 64.788±0.00 21.053±0.00 48.891±0.00 190.302±0.00 35.954±2.56

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001PK CIL_0001PK_0004 CGP 6:32934629-32953122

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002474 IEA antigen processing and presentation of peptide antigen via MHC class I
GO:0002503 IDA peptide antigen assembly with MHC class II protein complex
GO:0002504 IEA antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005764 IEA lysosome
GO:0005765 TAS lysosomal membrane
GO:0005770 IEA late endosome
GO:0005771 IEA multivesicular body
GO:0006461 IEA protein complex assembly
GO:0006955 IEA immune response
GO:0009986 IDA cell surface
GO:0010008 IEA endosome membrane
GO:0015031 IEA protein transport
GO:0016020 IDA:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016064 IEA immunoglobulin mediated immune response
GO:0019882 IEA antigen processing and presentation
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0023026 IDA MHC class II protein complex binding
GO:0042612 IEA MHC class I protein complex
GO:0042613 IEA:IDA MHC class II protein complex
GO:0045059 IEA positive thymic T cell selection
GO:0045582 IEA positive regulation of T cell differentiation
GO:0048839 IEA inner ear development
GO:0050778 IEA positive regulation of immune response
GO:0051085 IEA chaperone mediated protein folding requiring cofactor
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000037649 H2-DMa histocompatibility 2, class II, locus DMa protein_coding Mus_musculus

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