C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth differentiation factor 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038259 Gdf5 10090 - 2:155941023-155945367 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000040162 Gdf5-001 155941023-155945367 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000040162
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000040162 1.405±0.41 0.196±0.04 0.734±0.12 0.407±0.16 0.388±0.11 0.112±0.04 0.063±0.01 0.152±0.04 0.025±0.03 0.231±0.04 0.064±0.02 0.389±0.16 0.122±0.10 0.212±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008EI CIL_0008EI_0002 VISTA 2:155562263-156164147
CIL_0005FR CIL_0005FR_0002 CGP 2:155846894-155942750
CIL_0005FQ CIL_0005FQ_0002 CGP 2:155940728-155945367
CIL_0002I5 CIL_0002I5_0002 CGP 2:155941023-155998900

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002062 IGI chondrocyte differentiation
GO:0005102 IEA receptor binding
GO:0005125 IEA cytokine activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005886 IEA plasma membrane
GO:0007178 IGI transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0008083 IEA growth factor activity
GO:0030326 IMP embryonic limb morphogenesis
GO:0032332 IDA positive regulation of chondrocyte differentiation
GO:0035136 IMP forelimb morphogenesis
GO:0035137 IMP hindlimb morphogenesis
GO:0040007 IEA growth
GO:0040014 IMP regulation of multicellular organism growth
GO:0042802 IEA identical protein binding
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045666 IEA positive regulation of neuron differentiation
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:2001054 IMP negative regulation of mesenchymal cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002760 gdf5 growth differentiation factor 5 protein_coding Danio_rerio
ENSG00000125965 GDF5 growth differentiation factor 5 protein_coding Homo_sapiens

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