C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038664 Herc1 10090 + 9:66350450-66508775 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000042824 Herc1-001 66350526-66508775 protein_coding
  ENSMUST00000124969 Herc1-004 66468621-66476745 retained_intron
  ENSMUST00000130854 Herc1-006 66500254-66507593 retained_intron
  ENSMUST00000135159 Herc1-007 66451126-66464754 protein_coding
  ENSMUST00000135600 Herc1-005 66496555-66500520 retained_intron
  ENSMUST00000140487 Herc1-003 66441911-66452299 retained_intron
  ENSMUST00000144280 Herc1-002 66350450-66374070 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000042824
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000042824 4.427±1.37 4.341±1.43 3.915±1.59 15.066±1.25 5.191±1.44 4.223±1.84 3.588±0.91 3.688±1.45 3.941±2.26 4.530±2.24 2.628±0.61 9.508±2.79 3.574±1.74 5.532±3.14

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005575 ND cellular_component
GO:0010507 IMP negative regulation of autophagy
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0021702 IMP cerebellar Purkinje cell differentiation
GO:0031175 IMP neuron projection development
GO:0050885 IMP neuromuscular process controlling balance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077901 HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 protein_coding Danio_rerio
ENSG00000103657 HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 protein_coding Homo_sapiens

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