C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: bone morphogenetic protein 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039004 Bmp6 10090 + 13:38345716-38499728 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000171970 Bmp6-201 38345716-38499728 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000171970
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000171970 10.124±3.17 5.599±0.65 11.074±0.32 5.375±0.00 6.722±0.42 8.897±0.42 10.742±3.18 27.272±8.91 0.812±0.42 76.053±18.27 3.522±0.14 10.982±3.54 2.037±1.63 1.106±0.54

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007T6 CIL_0007T6_0002 VISTA 13:37870525-38472280
CIL_000380 CIL_000380_0002 CGP 13:38204939-38499728
CIL_000161 CIL_000161_0003 CGP 13:38345716-38528824

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0001649 IGI osteoblast differentiation
GO:0001654 IGI eye development
GO:0001822 IGI kidney development
GO:0001938 IDA positive regulation of endothelial cell proliferation
GO:0001958 IMP endochondral ossification
GO:0003323 IEA type B pancreatic cell development
GO:0005125 IEA cytokine activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0006879 IMP cellular iron ion homeostasis
GO:0006954 IEP inflammatory response
GO:0006955 IEA immune response
GO:0010039 IEA response to iron ion
GO:0010862 ISS positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0014823 IEA response to activity
GO:0030154 IMP cell differentiation
GO:0030501 IEA positive regulation of bone mineralization
GO:0030509 IDA BMP signaling pathway
GO:0030539 IGI male genitalia development
GO:0031988 IEA membrane-bounded vesicle
GO:0032026 IEA response to magnesium ion
GO:0032332 IEA positive regulation of chondrocyte differentiation
GO:0032349 IEA positive regulation of aldosterone biosynthetic process
GO:0032526 IEA response to retinoic acid
GO:0040007 IEA growth
GO:0045603 IDA positive regulation of endothelial cell differentiation
GO:0045666 IDA positive regulation of neuron differentiation
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0046982 ISO protein heterodimerization activity
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0051216 IEA cartilage development
GO:0051384 IEA response to glucocorticoid
GO:0060395 ISS SMAD protein signal transduction
GO:0070700 ISO BMP receptor binding
GO:0071260 IEA cellular response to mechanical stimulus
GO:2000860 IEA positive regulation of aldosterone secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015686 bmp6 bone morphogenetic protein 6 protein_coding Danio_rerio
ENSG00000153162 BMP6 bone morphogenetic protein 6 protein_coding Homo_sapiens

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