C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histamine receptor H3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039059 Hrh3 10090 - 2:180099465-180104488 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000056480 Hrh3-001 180099465-180104488 protein_coding
  ENSMUST00000163215 Hrh3-008 180099651-180104151 protein_coding
  ENSMUST00000164442 Hrh3-005 180100496-180104151 protein_coding
  ENSMUST00000165248 Hrh3-007 180099878-180104151 protein_coding
  ENSMUST00000165762 Hrh3-004 180099878-180104151 protein_coding
  ENSMUST00000166392 Hrh3-002 180100984-180103335 retained_intron
  ENSMUST00000166724 Hrh3-003 180100279-180104174 nonsense_mediated_decay
  ENSMUST00000171736 Hrh3-006 180100496-180104151 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000056480ENSMUST00000163215ENSMUST00000164442ENSMUST00000165248ENSMUST00000166392ENSMUST00000166724ENSMUST00000171736
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000056480 0.015±0.00 0.098±0.06 1.210±0.27 3.129±0.14 0.043±0.01 0.015±0.00 0.046±0.02 0.004±0.00 0.033±0.01 N/A 0.025±0.00 0.003±0.00 N/A
ENSMUST00000163215 N/A 0.078±0.05 N/A N/A N/A N/A 0.021±0.00 0.009±0.00 N/A N/A N/A 0.044±0.00 N/A
ENSMUST00000164442 N/A N/A N/A N/A 0.042±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000165248 N/A N/A N/A N/A 0.048±0.00 0.022±0.00 N/A N/A 0.023±0.00 N/A N/A N/A 0.468±0.00
ENSMUST00000166392 N/A 0.177±0.02 N/A N/A N/A N/A N/A N/A 0.037±0.00 N/A 0.124±0.02 0.009±0.00 N/A
ENSMUST00000166724 N/A 0.040±0.00 N/A N/A 0.033±0.00 0.044±0.00 0.025±0.00 0.003±0.00 N/A 0.064±0.00 N/A 0.005±0.00 N/A
ENSMUST00000171736 N/A 0.190±0.00 N/A N/A N/A N/A N/A N/A N/A 0.089±0.00 0.089±0.02 0.011±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001DR CIL_0001DR_0002 CGP 2:180070588-180104488
CIL_0001DS CIL_0001DS_0002 CGP 2:180099465-180162680

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001505 IEA regulation of neurotransmitter levels
GO:0004969 IEA histamine receptor activity
GO:0005886 IEA plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007194 IEA negative regulation of adenylate cyclase activity
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007420 IEA brain development
GO:0007612 IEA learning
GO:0007613 IEA memory
GO:0008144 IEA drug binding
GO:0014050 IEA negative regulation of glutamate secretion
GO:0014053 IEA negative regulation of gamma-aminobutyric acid secretion
GO:0014061 IEA regulation of norepinephrine secretion
GO:0014063 IEA negative regulation of serotonin secretion
GO:0014070 IEA response to organic cyclic compound
GO:0016021 IEA integral component of membrane
GO:0042755 IEA eating behavior
GO:0042756 IEA drinking behavior
GO:0043005 IEA neuron projection
GO:0043209 IEA myelin sheath
GO:0045776 IEA negative regulation of blood pressure
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0050890 IEA cognition

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000101180 HRH3 histamine receptor H3 protein_coding Homo_sapiens

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