C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: phosphatidylinositol binding clathrin assembly protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039361 Picalm 10090 + 7:90130232-90209447 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000049537 Picalm-201 90130232-90209447 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000049537
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000049537 15.088±2.24 21.798±8.43 35.959±6.53 22.398±11.92 12.050±3.02 18.850±4.26 9.212±0.67 28.019±2.02 33.561±23.88 17.423±4.00 15.532±1.44 14.211±7.88 20.629±8.23 11.381±6.51

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00004P CIL_00004P_0002 CGP 7:90130232-90265432

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005545 ISS 1-phosphatidylinositol binding
GO:0005622 IDA intracellular
GO:0005634 IEA nucleus
GO:0005794 IEA Golgi apparatus
GO:0005905 ISS coated pit
GO:0006898 ISS receptor-mediated endocytosis
GO:0007409 IMP axonogenesis
GO:0008283 ISS cell proliferation
GO:0010629 ISS negative regulation of gene expression
GO:0016020 IEA membrane
GO:0016188 IMP synaptic vesicle maturation
GO:0016197 IEA endosomal transport
GO:0030097 IMP hemopoiesis
GO:0030100 IEA regulation of endocytosis
GO:0030122 IEA AP-2 adaptor complex
GO:0030132 IEA clathrin coat of coated pit
GO:0030276 ISS clathrin binding
GO:0031623 IEA receptor internalization
GO:0031982 IDA vesicle
GO:0032050 IEA clathrin heavy chain binding
GO:0032880 IEA regulation of protein localization
GO:0035459 IMP cargo loading into vesicle
GO:0035615 ISS clathrin adaptor activity
GO:0043025 ISS neuronal cell body
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0048261 IEA negative regulation of receptor-mediated endocytosis
GO:0048268 IEA clathrin coat assembly
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048813 IMP dendrite morphogenesis
GO:0055072 ISS iron ion homeostasis
GO:0072583 IMP clathrin-mediated endocytosis
GO:0097418 ISS neurofibrillary tangle
GO:0097459 ISS iron ion import into cell
GO:1901216 ISS positive regulation of neuron death
GO:1902004 IMP positive regulation of beta-amyloid formation
GO:1902959 ISS regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
GO:1902961 IMP positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
GO:1902963 IMP negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012866 picalma phosphatidylinositol binding clathrin assembly protein a protein_coding Danio_rerio
ENSDARG00000014137 picalmb phosphatidylinositol binding clathrin assembly protein b protein_coding Danio_rerio
ENSG00000073921 PICALM phosphatidylinositol binding clathrin assembly protein protein_coding Homo_sapiens

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