C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: potassium voltage-gated channel, Isk-related subfamily, gene 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039672 Kcne2 10090 + 16:92292389-92298129 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047383 Kcne2-001 92292389-92298129 protein_coding
  ENSMUST00000113971 Kcne2-002 92295616-92298129 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047383ENSMUST00000113971
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047383 0.131±0.03 N/A N/A 4.890±3.19 N/A 0.719±0.10 N/A N/A N/A 12.690±0.35 N/A 0.894±0.51 0.115±0.08 0.012±0.00
ENSMUST00000113971 0.164±0.00 0.279±0.15 0.101±0.00 N/A 0.133±0.07 0.541±0.08 0.023±0.00 0.166±0.09 0.053±0.02 N/A 0.024±0.00 0.147±0.00 0.096±0.03 0.254±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ON CIL_0008ON_0002 VISTA 16:92040534-92642015
CIL_0007SX CIL_0007SX_0002 VISTA 16:92042784-92648394
CIL_0008OM CIL_0008OM_0002 VISTA 16:92044467-92645647
CIL_000788 CIL_000788_0002 CGP 16:92058322-92298129
CIL_0008ZS CIL_0008ZS_0002 VISTA 16:92110151-92716672
CIL_00094R CIL_00094R_0002 VISTA 16:92127453-92730131
CIL_000441 CIL_000441_0002 CGP 16:92292389-92313041

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005242 IEA inward rectifier potassium channel activity
GO:0005251 IEA delayed rectifier potassium channel activity
GO:0005515 IPI protein binding
GO:0005764 IEA lysosome
GO:0005886 IEA plasma membrane
GO:0007568 IEA aging
GO:0008076 IEA voltage-gated potassium channel complex
GO:0009986 IEA cell surface
GO:0010107 IEA potassium ion import
GO:0015459 IEA potassium channel regulator activity
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0034613 IMP cellular protein localization
GO:0035690 IEA cellular response to drug
GO:0042803 IEA protein homodimerization activity
GO:0043586 IEA tongue development
GO:0044325 IEA ion channel binding
GO:0060306 IEA regulation of membrane repolarization
GO:0060307 IMP regulation of ventricular cardiac muscle cell membrane repolarization
GO:0071435 IEA potassium ion export
GO:0071805 IMP potassium ion transmembrane transport
GO:0086002 IEA cardiac muscle cell action potential involved in contraction
GO:0086005 IMP ventricular cardiac muscle cell action potential
GO:0086009 IEA membrane repolarization
GO:0086011 IEA membrane repolarization during action potential
GO:0086091 IEA regulation of heart rate by cardiac conduction
GO:1901379 IEA regulation of potassium ion transmembrane transport
GO:1901800 IEA positive regulation of proteasomal protein catabolic process
GO:1901979 IEA regulation of inward rectifier potassium channel activity
GO:1902159 IEA regulation of cyclic nucleotide-gated ion channel activity
GO:1902259 IEA regulation of delayed rectifier potassium channel activity
GO:1902282 IEA voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
GO:2001257 IEA regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000159197 KCNE2 potassium voltage-gated channel, Isk-related family, member 2 protein_coding Homo_sapiens

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