C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: prostaglandin E receptor 4 (subtype EP4)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000039942 Ptger4 10090 - 15:5206661-5244187 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047379 Ptger4-001 5233399-5244187 protein_coding
  ENSMUST00000120563 Ptger4-002 5233399-5244172 protein_coding
  ENSMUST00000133966 Ptger4-003 5206661-5242710 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000047379ENSMUST00000120563
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000047379 9.445±6.01 2.181±0.56 2.867±0.28 8.436±3.99 20.524±1.56 1.014±0.08 1.956±0.27 0.580±0.33 2.663±0.29 11.190±5.54 1.404±0.00 0.228±0.05
ENSMUST00000120563 4.890±2.40 0.763±0.30 2.192±0.06 4.049±0.74 7.394±1.38 0.794±0.20 1.098±0.18 0.472±0.15 1.618±0.53 3.833±1.30 1.659±0.11 0.242±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004957 TAS:ISS prostaglandin E receptor activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0006955 IEA immune response
GO:0007188 ISS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007189 TAS adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007254 ISS JNK cascade
GO:0009612 IEA response to mechanical stimulus
GO:0016021 IEA integral component of membrane
GO:0030278 IMP regulation of ossification
GO:0032496 IMP response to lipopolysaccharide
GO:0033624 ISS negative regulation of integrin activation
GO:0042093 IDA T-helper cell differentiation
GO:0050710 IMP negative regulation of cytokine secretion
GO:0050715 IDA positive regulation of cytokine secretion
GO:0050728 IGI:ISS negative regulation of inflammatory response
GO:0050729 IDA positive regulation of inflammatory response
GO:0051492 IDA regulation of stress fiber assembly
GO:0060348 ISS bone development
GO:0070371 ISS ERK1 and ERK2 cascade
GO:0071260 IEP cellular response to mechanical stimulus
GO:2000420 ISS negative regulation of eosinophil extravasation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000035415 ptger4b prostaglandin E receptor 4 (subtype EP4) b protein_coding Danio_rerio
ENSDARG00000059236 ptger4a prostaglandin E receptor 4 (subtype EP4) a protein_coding Danio_rerio
ENSG00000171522 PTGER4 prostaglandin E receptor 4 (subtype EP4) protein_coding Homo_sapiens

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