C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: prostaglandin E receptor 4 (subtype EP4)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000047379 Ptger4-001 ENSMUSG00000039942 10090 - 15:5233399-5244187 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000047379
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000047379 9.445±6.01 2.181±0.56 2.867±0.28 8.436±3.99 20.524±1.56 1.014±0.08 1.956±0.27 0.580±0.33 2.663±0.29 11.190±5.54 1.404±0.00 0.228±0.05

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004957 TAS:ISS prostaglandin E receptor activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0006955 IEA immune response
GO:0007188 ISS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007189 TAS adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007254 ISS JNK cascade
GO:0009612 IEA response to mechanical stimulus
GO:0016021 IEA integral component of membrane
GO:0030278 IMP regulation of ossification
GO:0032496 IMP response to lipopolysaccharide
GO:0033624 ISS negative regulation of integrin activation
GO:0042093 IDA T-helper cell differentiation
GO:0050710 IMP negative regulation of cytokine secretion
GO:0050715 IDA positive regulation of cytokine secretion
GO:0050728 IGI:ISS negative regulation of inflammatory response
GO:0050729 IDA positive regulation of inflammatory response
GO:0051492 IDA regulation of stress fiber assembly
GO:0060348 ISS bone development
GO:0070371 ISS ERK1 and ERK2 cascade
GO:0071260 IEP cellular response to mechanical stimulus
GO:2000420 ISS negative regulation of eosinophil extravasation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000302472 PTGER4-001 protein_coding Homo_sapiens 0 1567
ENST00000328411 PTGER4P2-001 processed_pseudogene Homo_sapiens 0 202
ENST00000458150 PTGER4P3-001 processed_pseudogene Homo_sapiens 0 196
ENST00000512578 PTGER4-004 processed_transcript Homo_sapiens 0 664
ENST00000514343 PTGER4-003 processed_transcript Homo_sapiens 0 817

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