C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: membrane associated guanylate kinase, WW and PDZ domain containing 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040003 Magi2 10090 + 5:19227046-20704798 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000088516 Magi2-003 19227046-20702903 protein_coding
  ENSMUST00000101558 Magi2-001 19907518-20704798 protein_coding
  ENSMUST00000115267 Magi2-002 19907861-20702938 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000088516ENSMUST00000101558ENSMUST00000115267
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000088516 N/A N/A N/A 0.154±0.00 0.124±0.00 N/A 0.345±0.00 0.012±0.00 N/A N/A 0.188±0.00 N/A 0.981±0.05
ENSMUST00000101558 0.551±0.02 0.249±0.09 10.884±3.66 0.599±0.33 0.185±0.07 0.239±0.18 1.164±0.17 0.062±0.04 0.243±0.00 0.118±0.00 0.578±0.33 0.150±0.08 0.390±0.00
ENSMUST00000115267 N/A 0.126±0.00 7.651±0.00 0.084±0.00 0.167±0.03 N/A N/A 0.012±0.00 N/A 0.058±0.02 0.306±0.14 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002092 ISS positive regulation of receptor internalization
GO:0004871 IPI signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005770 ISS late endosome
GO:0005886 IDA plasma membrane
GO:0005923 ISS tight junction
GO:0007165 IPI signal transduction
GO:0008285 ISS negative regulation of cell proliferation
GO:0010976 ISS positive regulation of neuron projection development
GO:0014069 ISS postsynaptic density
GO:0016482 ISS cytoplasmic transport
GO:0019902 ISS phosphatase binding
GO:0030159 ISS receptor signaling complex scaffold activity
GO:0030165 ISS PDZ domain binding
GO:0030336 ISS negative regulation of cell migration
GO:0030425 ISS dendrite
GO:0031697 ISS beta-1 adrenergic receptor binding
GO:0032516 ISS positive regulation of phosphoprotein phosphatase activity
GO:0032926 IDA negative regulation of activin receptor signaling pathway
GO:0036057 ISS slit diaphragm
GO:0038180 ISS nerve growth factor signaling pathway
GO:0043113 ISS receptor clustering
GO:0043234 ISS protein complex
GO:0045202 ISS synapse
GO:0046332 IPI SMAD binding
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051291 ISS protein heterooligomerization
GO:0051898 ISS negative regulation of protein kinase B signaling
GO:0060395 IDA SMAD protein signal transduction
GO:0070699 IPI type II activin receptor binding
GO:0071850 ISS mitotic cell cycle arrest
GO:0072015 ISS glomerular visceral epithelial cell development
GO:1990090 ISS cellular response to nerve growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021590 magi2 membrane associated guanylate kinase, WW and PDZ domain containing 2 protein_coding Danio_rerio
ENSDARG00000073769 MAGI2 (2 of 2) membrane associated guanylate kinase, WW and PDZ domain containing 2 protein_coding Danio_rerio
ENSG00000187391 MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 protein_coding Homo_sapiens

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