C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: membrane associated guanylate kinase, WW and PDZ domain containing 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000088516 Magi2-003 ENSMUSG00000040003 10090 + 5:19227046-20702903 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastColonKidneyLiverOvaryTestisENSMUST00000088516
Transcript ID Breast Colon Kidney Liver Ovary Testis
ENSMUST00000088516 0.154±0.00 0.124±0.00 0.345±0.00 0.012±0.00 0.188±0.00 0.981±0.05

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002092 ISS positive regulation of receptor internalization
GO:0004871 IPI signal transducer activity
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005770 ISS late endosome
GO:0005886 IDA plasma membrane
GO:0005923 ISS tight junction
GO:0007165 IPI signal transduction
GO:0008285 ISS negative regulation of cell proliferation
GO:0010976 ISS positive regulation of neuron projection development
GO:0014069 ISS postsynaptic density
GO:0016482 ISS cytoplasmic transport
GO:0019902 ISS phosphatase binding
GO:0030159 ISS receptor signaling complex scaffold activity
GO:0030165 ISS PDZ domain binding
GO:0030336 ISS negative regulation of cell migration
GO:0030425 ISS dendrite
GO:0031697 ISS beta-1 adrenergic receptor binding
GO:0032516 ISS positive regulation of phosphoprotein phosphatase activity
GO:0032926 IDA negative regulation of activin receptor signaling pathway
GO:0036057 ISS slit diaphragm
GO:0038180 ISS nerve growth factor signaling pathway
GO:0043113 ISS receptor clustering
GO:0043234 ISS protein complex
GO:0045202 ISS synapse
GO:0046332 IPI SMAD binding
GO:0048471 ISS perinuclear region of cytoplasm
GO:0051291 ISS protein heterooligomerization
GO:0051898 ISS negative regulation of protein kinase B signaling
GO:0060395 IDA SMAD protein signal transduction
GO:0070699 IPI type II activin receptor binding
GO:0071850 ISS mitotic cell cycle arrest
GO:0072015 ISS glomerular visceral epithelial cell development
GO:1990090 ISS cellular response to nerve growth factor stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000044423 magi1b-201 protein_coding Danio_rerio 0.00009 55
ENSDART00000103969 magi1b-001 protein_coding Danio_rerio 0.00009 55
ENST00000354212 MAGI2-001 protein_coding Homo_sapiens 0 5526
ENST00000419488 MAGI2-002 protein_coding Homo_sapiens 0 3657
ENST00000519748 MAGI2-004 retained_intron Homo_sapiens 0 2054
ENST00000520379 MAGI2-005 retained_intron Homo_sapiens 0 2141
ENST00000522342 MAGI2-009 processed_transcript Homo_sapiens 0 695
ENST00000522391 MAGI2-003 protein_coding Homo_sapiens 0 5995
ENST00000524268 MAGI2-007 retained_intron Homo_sapiens 0 424
ENST00000524316 MAGI2-006 processed_transcript Homo_sapiens 0 368
ENST00000535697 MAGI2-201 protein_coding Homo_sapiens 0 2750

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