C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cyclin-dependent kinase 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000040274 Cdk6 10090 + 5:3343893-3523218 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000042410 Cdk6-201 3344312-3522225 protein_coding
  ENSMUST00000165117 Cdk6-202 3343893-3523218 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000042410ENSMUST00000165117
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000042410 1.675±0.59 1.178±0.50 0.102±0.00 1.342±0.60 2.303±0.78 0.642±0.23 0.981±0.49 1.094±0.11 1.238±0.00 0.052±0.02 1.564±0.49 0.288±0.12 0.897±0.43
ENSMUST00000165117 2.713±1.70 1.521±0.60 0.091±0.00 1.382±1.06 3.417±0.80 1.807±0.00 1.472±0.38 1.611±0.45 5.887±0.78 0.091±0.04 4.389±1.36 0.415±0.22 0.384±0.22

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000307 IEA cyclin-dependent protein kinase holoenzyme complex
GO:0001726 IEA ruffle
GO:0001954 IEA positive regulation of cell-matrix adhesion
GO:0002244 IMP hematopoietic progenitor cell differentiation
GO:0003323 IEA type B pancreatic cell development
GO:0004693 IEA cyclin-dependent protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0007049 IEA cell cycle
GO:0007219 IDA Notch signaling pathway
GO:0009615 IEA response to virus
GO:0010468 IEA regulation of gene expression
GO:0010628 IDA positive regulation of gene expression
GO:0016301 IDA kinase activity
GO:0030097 IMP hemopoiesis
GO:0030332 IEA cyclin binding
GO:0033077 IMP T cell differentiation in thymus
GO:0042063 IEA gliogenesis
GO:0043697 IEA cell dedifferentiation
GO:0045638 IEA negative regulation of myeloid cell differentiation
GO:0045646 IEA regulation of erythrocyte differentiation
GO:0045668 IEA negative regulation of osteoblast differentiation
GO:0045786 IEA negative regulation of cell cycle
GO:0048146 IEA positive regulation of fibroblast proliferation
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0051301 IEA cell division
GO:0060218 IMP hematopoietic stem cell differentiation
GO:2000773 IEA negative regulation of cellular senescence

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000070228 cdk6 cyclin-dependent kinase 6 protein_coding Danio_rerio
ENSG00000105810 CDK6 cyclin-dependent kinase 6 protein_coding Homo_sapiens

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